Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29350840 | 0.78 | MEN1 (0.57) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL14438168 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL904817 | 0.78 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL2954 | 0.78 | MEN1 (0.57) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL7607425 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL7606134 | 0.78 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL4884291 | 0.76 | MEN1 (0.56) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL12247551 | 0.75 | ALDH1A1 (0.78) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL7872101 | 0.75 | RAB9A (0.76) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL24437289 | 0.73 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130079518-A1 | REGIOSELECTIVE PREPARATION OF SUBSTITUTED PYRIMIDINES | LINZ GUENTER (DE) | 2013-03-28 | — | — | US | claimed |
| US-8372974-B2 | Regioselective preparation of substituted pyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-12 | — | — | US | claimed |
| US-20110060141-A1 | REGIOSELECTIVE PREPARATION OF SUBSTITUTED PYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-10 | — | — | US | claimed |
| US-7897560-B2 | Plasma protein affinity tags | NOVO NORDISK A/S (DK) | 2011-03-01 | — | — | US | claimed |
| US-20100184641-A1 | Novel Plasma Protein Affinity Tags | NOVO NORDISK A/S (DK) | 2010-07-22 | — | — | US | claimed |
| US-20070105750-A1 | Novel plasma protein affinity tags | NOVO NORDISK A/S (DK) | 2007-05-10 | — | — | US | claimed |
| EP-1667724-A2 | ALBUMIN-BINDING DERIVATIVES OF THERAPEUTIC PEPTIDES | NOVO NORDISK A/S (DK) | 2006-06-14 | — | — | EP | claimed |
| WO-2005028516-A2 | ALBUMIN-BINDING DERIVATIVES OF THERAPEUTIC PEPTIDES | NOVO NORDISK A/S (DK) | 2005-03-31 | — | — | WO | claimed |
| US-6465650-B1 | INTERMEDIATE STEPS IN PREPARING PEPTIDE NUCLEIC ACIDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-10-15 | — | — | US | claimed |
| EP-0247573-A2 | Amino acid benzotriazinyl esters, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-02 | — | — | EP | claimed |
| US-4242507-A | Sulfonic acid esters | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-12-30 | — | — | US | claimed |
| EP-1995254-B1 | METHOD OF PRODUCING PEPTIDES | KANEKA CORP (JP) | 2019-04-03 | — | — | EP | disclosed |
| US-9346850-B2 | Method of producing peptide | KANEKA CORPORATION (JP) | 2016-05-24 | — | — | US | disclosed |
| US-20150183818-A1 | PROCESS FOR PREPARING DIASTEREOMERICALLY ENRICHED PHOSPHORAMIDATE DERIVATIVES OF NUCLEOSIDE COMPOUNDS FOR TREATMENT OF VIRAL INFECTIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-07-02 | — | — | US | disclosed |
| US-8933227-B2 | Selective synthesis of functionalized pyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-01-13 | — | — | US | disclosed |
| EP-0247573-A3 | AMINO ACID BENZOTRIAZINYL ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-09-21 | — | — | EP | disclosed |
| EP-0247573-A2 | Amino acid benzotriazinyl esters, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-02 | — | — | EP | disclosed |
| EP-0247573-A2 | Amino acid benzotriazinyl esters, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-02 | — | — | EP | disclosed |
| US-4474767-A | Peptide and pseudopeptide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-10-02 | — | — | US | disclosed |
| EP-0109142-A2 | Peptide and pseudopeptide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184641-A1 | Novel Plasma Protein Affinity Tags | CD2BP2, HDLBP, SERPINA6 | SMN1; SMN2 3053/4885ALDH1A1 4651/4885CYP1A2 4749/4885 |
| US-20070105750-A1 | Novel plasma protein affinity tags | CD2BP2, HDLBP, SERPINA6 | SMN1; SMN2 3053/4885ALDH1A1 4651/4885CYP1A2 4749/4885 |
| US-20150183818-A1 | PROCESS FOR PREPARING DIASTEREOMERICALLY ENRICHED PHOSPHORAMIDATE DERIVATIVES OF NUCLEOSIDE COMPOUNDS FOR TREATMENT OF VIRAL INFECTIONS | SAMHD1, TYMP, PNP | SMN1; SMN2 433/4885ALDH1A1 1868/4885CYP1A2 3459/4885 |
| US-20110060141-A1 | REGIOSELECTIVE PREPARATION OF SUBSTITUTED PYRIMIDINES | TYMS, DPYD, TYMP | SMN1; SMN2 2143/4885ALDH1A1 751/4885CYP1A2 261/4885 |
| US-20130079518-A1 | REGIOSELECTIVE PREPARATION OF SUBSTITUTED PYRIMIDINES | TYMS, DPYD, TYMP | SMN1; SMN2 2083/4885ALDH1A1 775/4885CYP1A2 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.