Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.44 |
| ▸ | AHCY | P23526 | 2/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29540248 | 0.95 | DOT1L (0.47) | DOT1LADORA3AHCYPRMT5WDR77 | |
| SCHEMBL29540557 | 0.82 | DOT1L (0.45) | DOT1LADORA3AHCYPRMT5WDR77 | |
| SCHEMBL16289825 | 0.82 | DOT1L (0.45) | DOT1LADORA3AHCYPRMT5WDR77 | |
| SCHEMBL30861853 | 0.80 | HSP90B1 (0.55) | ADORA3AHCYADORA2BHSP90B1HSP90AA1 | |
| SCHEMBL30744251 | 0.79 | ADORA3 (0.53) | DOT1LADORA3AHCYADORA2BHSP90B1 | |
| SCHEMBL4314015 | 0.70 | ADORA1 (0.61) | ADORA1 | |
| SCHEMBL29365543 | 0.70 | P2RY1 (0.55) | ADORA1 | |
| SCHEMBL25607786 | 0.70 | P2RY1 (0.55) | ADORA1 | |
| SCHEMBL22799204 | 0.69 | AHCY (0.55) | AHCYADORA2BHSP90B1ADORA2A | |
| SCHEMBL16255813 | 0.69 | P2RY1 (0.52) | ADORA3AHCYADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974563-A1 | CYCLIC PEPTIDES | Chugai Seiyaku Kabushiki Kaisha (JP) | 2022-03-30 | — | — | EP | disclosed |