Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | PRKCA | P17252 | 1/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | PRKACG | P22612 | 1/20 | 0.46 |
| ▸ | PRKACB | P22694 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29539927 | 0.82 | IKBKB (0.67) | ABL1EGFRPRKCAPRKCDHDAC8 | |
| SCHEMBL27739764 | 0.81 | HDAC8 (0.54) | ABL1EGFRPRKCAPRKCDHDAC8 | |
| SCHEMBL27739765 | 0.81 | ABL1 (0.53) | ABL1EGFRPRKCAPRKCDHDAC8 | |
| SCHEMBL29540283 | 0.80 | IKBKB (0.65) | ABL1EGFRPRKCAPRKCDHDAC8 | |
| SCHEMBL29540438 | 0.79 | IKBKB (0.71) | ABL1EGFRPRKCAPRKCDHDAC8 | |
| SCHEMBL4377891 | 0.76 | DGAT1 (0.51) | ABL1EGFRPRKCAPRKCDHDAC8 | |
| SCHEMBL30565323 | 0.76 | PRKCZ (0.52) | ABL1EGFRPRKCAPRKCDHDAC8 | |
| SCHEMBL21621267 | 0.74 | IKBKB (0.59) | HDAC8HDAC6CDK4GSK3BCDK2 | |
| SCHEMBL30299645 | 0.74 | IKBKB (0.59) | HDAC8HDAC6CDK4GSK3BCDK2 | |
| SCHEMBL1088926 | 0.73 | HRH4 (0.61) | CDK4GSK3BCDK2DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110418789-B | Derivatives of N-cycloalkyl/heterocycloalkyl-4- (imidazo [1,2-a ] pyridine) pyrimidin-2-amines as therapeutic agents | 常州千红生化制药股份有限公司 | 2022-03-25 | — | — | CN | disclosed |