SCHEMBL29540447

SCHEMBL29540447

C[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)CNC(=O)[C@@H](N)CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CAPN1 P07384 8/20 0.49
▸ CTSB P07858 3/20 0.44
▸ OPRM1 P35372 1/20 0.40
▸ OPRD1 P41143 1/20 0.40
▸ CALCRL Q16602 3/20 0.40
▸ APLNR P35414 1/20 0.40
▸ BDKRB2 P30411 2/20 0.39
▸ CXCR4 P61073 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30307615 0.95 OPRM1 (0.46) CAPN1CTSBOPRM1OPRD1CALCRL
SCHEMBL29760917 0.94 CAPN1 (0.54) CAPN1CTSBCALCRL
SCHEMBL31259022 0.92 CAPN1 (0.52) CAPN1CTSBOPRM1OPRD1CALCRL
SCHEMBL29554458 0.91 CAPN1 (0.54) CAPN1CTSBOPRM1OPRD1CALCRL
SCHEMBL32677766 0.91 CAPN1 (0.48) CAPN1CTSBOPRM1OPRD1CALCRL
SCHEMBL32677764 0.91 CAPN1 (0.48) CAPN1CTSBOPRM1OPRD1CALCRL
SCHEMBL29760912 0.90 CAPN1 (0.54) CAPN1CTSBOPRM1OPRD1CALCRL
SCHEMBL29691750 0.90 CAPN1 (0.54) CAPN1CTSBOPRM1OPRD1CALCRL
SCHEMBL29358088 0.90 APLNR (0.46) CAPN1OPRM1OPRD1APLNRBDKRB2
SCHEMBL29760911 0.89 CAPN1 (0.56) CAPN1CTSBCALCRLCXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12453823-B2 Autoinjector Sanofi-Avents Deutschland GmbH (DE) 2025-10-28 — — US disclosed
US-12440152-B2 Supplementary device for a manually operable injection device SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2025-10-14 — — US disclosed
US-20250213795-A1 Autoinjector SANOFI AVENTIS DEUTSCHLAND (DE) 2025-07-03 — — US disclosed
US-20250152846-A1 AUTOINJECTOR SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2025-05-15 — — US disclosed
US-12251548-B2 Medicament delivery device with use indicator SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2025-03-18 — — US disclosed
US-12220444-B2 Treatment of hyperinsulinemic hypoglycemia with GLP-1 antagonist exendin(9-39) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-02-11 — — US disclosed
US-20240342375-A1 Medicament Delivery Device and Actuation Mechanism for a Drug Delivery Device SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2024-10-17 — — US disclosed
US-20240342385-A1 Auto-Injector SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2024-10-17 — — US disclosed
WO-2023231433-A1 LONG-ACTING EXENDIN-9-39 AND USE THEREOF IN HYPOGLYCEMIA TREATMENT AND AS DRUG FOR TREATING HYPOGLYCEMIA 南京盛德瑞尔医药科技有限公司 2023-12-07 — — WO disclosed
US-20230346890-A1 TREATMENT OF POST-BARIATRIC HYPOGLYCEMIA WITH GLP-1 ANTAGONISTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2023-11-02 — — US disclosed
US-11419918-B2 Treatment of biliary cirrhosis based on oxyntomodulin analogue GLP-1R/GCGR dual-target agonist peptide SHENZHEN TURIER BIOTECH CO., LTD. 2022-08-23 — — US disclosed
US-20220241511-A1 Injection Device SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2022-08-04 — — US disclosed
US-20220096005-A1 Supplementary Device for a Manually Operable Injection Device SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2022-03-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11419918-B2 Treatment of biliary cirrhosis based on oxyntomodulin analogue GLP-1R/GCGR dual-target agonist peptide GCGR, GLP1R, GIPR CAPN1 2190/4885CTSB 751/4885OPRM1 897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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