Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LOX | P28300 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.39 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263572 | 0.67 | CYP1A2 (0.47) | GAAKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL6735947 | 0.65 | KMT2A (0.41) | GAAMGLLKMT2AALDH1A1MEN1 | |
| SCHEMBL8871184 | 0.65 | GAA (0.45) | GAAMGLLKMT2AALDH1A1MEN1 | |
| SCHEMBL4282424 | 0.64 | MEN1 (0.47) | GAAKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL1722780 | 0.63 | GSK3B (0.71) | GAAMGLLKMT2AALDH1A1MEN1 | |
| SCHEMBL10134037 | 0.63 | KMT2A (0.39) | GAAMGLLKMT2AALDH1A1MEN1 | |
| SCHEMBL12291974 | 0.63 | MAPT (0.64) | GAAKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL16280099 | 0.63 | MGLL (0.62) | GAAMGLLKMT2AALDH1A1MEN1 | |
| SCHEMBL6731372 | 0.63 | KMT2A (0.64) | GAAKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL447260 | 0.62 | GAA (1.00) | GAAMGLLKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130143916-A1 | COMPOUND LIBRARIES MADE THROUGH PHOSPHINE-CATALYZED ANNULATION/TEBBE/DIELS-ALDER REACTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-06-06 | — | — | US | claimed |
| EP-0778023-B1 | Product comprising rapamycin or particular derivatives and an NMDA or AMPA antagonist for use for the treatment of epilepsy or Huntington's Disease, and the use of rapamycin or particular derivatives for the manufacture of a medicament for the treatment of epilepsy or Huntington's Disease. | WYETH CORP (US) | 2003-03-12 | — | — | EP | claimed |
| EP-1002535-A1 | New use of glutamate antagonists for the treatment of cancer | Ikonomidou, Hrissanthi (DE) | 2000-05-24 | — | — | EP | claimed |
| EP-0778023-A1 | Neuroprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-06-11 | — | — | EP | claimed |
| US-4252719-A | REMOVAL OF A TERTIARY HYDROGEN FROM A 5-A-STEROID BY CHLORINATING THE STEROID BEING FIRST ESTERIFIED BY AN IODOARYL-CONTAINING ESTERIFICATION AGENT | RESEARCH CORPORATION (US) | 1981-02-24 | — | — | US | claimed |
| JP-9183727-A | — | — | None | — | — | JP | disclosed |
| EP-4312851-B1 | MECHANOCHROMIC PRESSURE SENSOR FOR SAFE AND EFFECTIVE TISSUE HANDLING IN MINIMALLY INVASIVE SURGERY | FONDAZIONE ST ITALIANO TECNOLOGIA (IT) | 2024-10-09 | — | — | EP | disclosed |
| US-20240180576-A1 | MECHANOCHROMIC PRESSURE SENSOR FOR SAFE AND EFFECTIVE TISSUE HANDLING IN MINIMALLY INVASIVE SURGERY | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2024-06-06 | — | — | US | disclosed |
| WO-2022201024-A1 | MECHANOCHROMIC PRESSURE SENSOR FOR SAFE AND EFFECTIVE TISSUE HANDLING IN MINIMALLY INVASIVE SURGERY | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2022-09-29 | — | — | WO | disclosed |
| US-10160766-B1 | Benzopyranyl tetracycle compound and pharmaceutical composition having excellent anti-inflammatory effect comprising the same | SPARK BIOPHARMA, INC. (KR) | 2018-12-25 | — | — | US | disclosed |
| EP-0968223-B1 | BIOCONJUGATION OF MACROMOLECULES | SIGMA ALDRICH CO LLC (US) | 2016-12-21 | — | — | EP | disclosed |
| EP-2256133-B1 | Bioconjugation of macromolecules | SIGMA ALDRICH CO LLC (US) | 2016-12-14 | — | — | EP | disclosed |
| EP-0778023-A1 | Neuroprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-06-11 | — | — | EP | disclosed |
| EP-0778023-A1 | Neuroprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-06-11 | — | — | EP | disclosed |
| EP-0710110-A1 | RAPAMYCIN CONJUGATES AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1996-05-08 | — | — | EP | disclosed |
| EP-0676471-A2 | Effector proteins of rapamycin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-10-11 | — | — | EP | disclosed |
| WO-1994025022-A1 | RAPAMYCIN CONJUGATES AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1994-11-10 | — | — | WO | disclosed |
| WO-1994025072-A1 | RAPAMYCIN CONJUGATES AND ANTIBODIES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-11-10 | — | — | WO | disclosed |
| US-4396750-A | Process for synthesizing silylated polyalkenamers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1983-08-02 | — | — | US | disclosed |
| US-4252719-A | REMOVAL OF A TERTIARY HYDROGEN FROM A 5-A-STEROID BY CHLORINATING THE STEROID BEING FIRST ESTERIFIED BY AN IODOARYL-CONTAINING ESTERIFICATION AGENT | RESEARCH CORPORATION (US) | 1981-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10160766-B1 | Benzopyranyl tetracycle compound and pharmaceutical composition having excellent anti-inflammatory effect comprising the same | HMGB1, HMGB2, HMGB3 | GAA 3006/4885MGLL 4789/4885KMT2A 3284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.