Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 20/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18890288 | 1.00 | GLS (0.57) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL21336454 | 1.00 | GLS (0.57) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL29543664 | 0.87 | GLS (0.57) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL18890324 | 0.87 | GLS (0.57) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL17309281 | 0.81 | GLS (0.55) | GLS | |
| SCHEMBL17309177 | 0.79 | GLS (0.61) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL18933614 | 0.79 | GLS (0.61) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL18946019 | 0.76 | HRH4 (0.51) | GLS | |
| SCHEMBL18945889 | 0.76 | GLS (0.75) | GLS | |
| SCHEMBL18951919 | 0.75 | GLS (0.59) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349967-B | 1,3, 4-thiadiazole compounds and their use in the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2022-02-15 | — | — | CN | disclosed |