SCHEMBL2954428

SCHEMBL2954428

CCc1c(N)ccc(C)c1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 3/20 0.42
NOS3 P29474 2/20 0.42
S100B P04271 1/20 0.36
POLB P06746 3/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP3A4 P08684 6/20 0.36
ALDH1A1 P00352 4/20 0.36
TDP1 Q9NUW8 4/20 0.36
TSHR P16473 3/20 0.36
CASP1 P29466 1/20 0.36
SKP2 Q13309 1/20 0.35
PIK3CA P42336 1/20 0.35
ESR1 P03372 2/20 0.32
MAPT P10636 1/20 0.32
AR P10275 1/20 0.32
ESR2 Q92731 1/20 0.32
TP53 P04637 1/20 0.32
THRB P10828 1/20 0.32
ALOX15 P16050 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847085 0.85 CYP3A4 (0.43) NOS2NOS3S100BPOLBKDM4E
SCHEMBL109396 0.83 NOS2 (0.48) NOS2NOS3S100BPOLBKDM4E
SCHEMBL3668922 0.83 CYP3A4 (0.37) NOS2NOS3S100BPOLBCYP3A4
SCHEMBL9469338 0.82 NOS2 (0.46) NOS2NOS3S100BPOLBKDM4E
SCHEMBL6356384 0.81 NOS3 (0.42) NOS2NOS3S100BPOLBKDM4E
SCHEMBL30324471 0.81 NOS3 (0.42) NOS2NOS3S100BPOLBKDM4E
SCHEMBL9359662 0.80 SKP2 (0.53) NOS2S100BPOLBKDM4ECYP3A4
Ammonia Solution, Strong SCHEMBL3635517 0.80 NOS2 (0.44) NOS2NOS3S100BPOLBKDM4E
SCHEMBL3456090 0.79 NOS2 (0.43) NOS2NOS3POLBKDM4ETSHR
SCHEMBL3222203 0.79 ALDH1A1 (0.39) NOS2NOS3S100BPOLBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7749625-B2 Fuel for fuel cell, fuel cell and application thereof KURITA WATER INDUSTRIES LTD. (JP) 2010-07-06 US disclosed
US-20080233438-A1 Fuel for fuel cell, fuel cell and application thereof KURITA WATER INDUSTRIES LTD. (JP) 2008-09-25 US disclosed
EP-1705740-A1 FUEL FOR FUEL CELL, FUEL CELL AND APPLICATION THEREOF Kurita Water Industries Ltd. (JP) 2006-09-27 EP disclosed
US-4173645-A INSECTICIDES, MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-11-06 US disclosed