Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 4/20 | 0.37 |
| ▸ | EGFR | P00533 | 4/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 11/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29544843 | 0.93 | FGFR1 (0.38) | TYK2EGFRFGFR1FGFR4ERBB2 | |
| SCHEMBL29544745 | 0.89 | TYK2 (0.36) | TYK2 | |
| SCHEMBL29544750 | 0.89 | EGFR (0.40) | EGFRFGFR1FGFR4FGFR2ERBB2 | |
| SCHEMBL29544735 | 0.86 | CCNT1 (0.34) | TYK2EGFR | |
| SCHEMBL29544781 | 0.86 | CCNT1 (0.34) | TYK2EGFR | |
| SCHEMBL29545142 | 0.83 | CSF1R (0.39) | TYK2EGFR | |
| SCHEMBL29544647 | 0.83 | EGFR (0.40) | EGFRFGFR1FGFR4ERBB2 | |
| SCHEMBL29544407 | 0.82 | CCNT1 (0.34) | TYK2EGFR | |
| SCHEMBL29544972 | 0.81 | EGFR (0.37) | TYK2EGFR | |
| SCHEMBL29545092 | 0.81 | EGFR (0.39) | TYK2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |