Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509694 | 0.82 | HTT (0.68) | HTTPKMLMNAKMT2AALDH1A1 | |
| SCHEMBL8536244 | 0.81 | HTT (0.66) | HTTPKMLMNAKMT2AALDH1A1 | |
| SCHEMBL16603070 | 0.80 | PKM (0.72) | HTTPKMLMNAKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL20984252 | 0.79 | HTT (0.64) | HTTPKMLMNAKMT2AALDH1A1 | |
| Bromide SCHEMBL20984908 | 0.79 | HTT (0.64) | HTTPKMLMNAKMT2AALDH1A1 | |
| SCHEMBL15257085 | 0.79 | MAPT (0.53) | HTTKMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL21280225 | 0.78 | HTT (0.62) | HTTPKMLMNAKMT2AALDH1A1 | |
| SCHEMBL962472 | 0.78 | HTT (0.62) | HTTPKMLMNAKMT2AALDH1A1 | |
| SCHEMBL13815362 | 0.78 | LMNA (0.78) | HTTPKMLMNAKMT2AALDH1A1 | |
| SCHEMBL19669453 | 0.78 | MAPT (0.51) | HTTPKMLMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |