Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 7/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18555261 | 1.00 | CFD (0.47) | CFDGRIN2BKMT2ACREBBPSMN1; SMN2 | |
| SCHEMBL29545636 | 0.89 | ICMT (0.48) | CFDGRIN2BKMT2AALDH1A1P2RY12 | |
| SCHEMBL18554993 | 0.89 | ICMT (0.48) | CFDGRIN2BKMT2AALDH1A1P2RY12 | |
| SCHEMBL24287612 | 0.88 | CNR2 (0.45) | CFDKMT2AALDH1A1 | |
| SCHEMBL17024799 | 0.87 | CFD (0.41) | CFDKMT2ACREBBPSMN1; SMN2ALDH1A1 | |
| SCHEMBL29545109 | 0.87 | CFD (0.41) | CFDKMT2ACREBBPSMN1; SMN2ALDH1A1 | |
| SCHEMBL17037526 | 0.87 | CFD (0.43) | CFDKMT2ACREBBPSMN1; SMN2ALDH1A1 | |
| SCHEMBL24287868 | 0.86 | CFD (0.44) | CFDCREBBPSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL18578356 | 0.85 | CFD (0.45) | CFDGRIN2BKMT2ACREBBPSMN1; SMN2 | |
| SCHEMBL29544920 | 0.85 | CFD (0.45) | CFDGRIN2BKMT2ACREBBPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051339-A1 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS | ALEXION PHARMACEUTICALS, INC. (US) | 2025-02-13 | — | — | US | disclosed |
| CN-118556060-A | Synthesis method of complement factor D inhibitor | 阿雷克森制药公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-114044800-A | Aryl, heteroaryl and heterocyclic compounds for the treatment of medical disorders | 艾其林医药公司 | 2022-02-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051339-A1 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS | CFD, CFH, TFPI | CFD 1/4885GRIN2B 3984/4885KMT2A 3600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.