Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.47 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1178289 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TSHRDDB1CRBNIKZF3 | |
| SCHEMBL1178291 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TSHRDDB1CRBNIKZF3 | |
| SCHEMBL17362471 | 0.89 | ALDH1A1 (0.45) | ALDH1A1TSHRDDB1CRBNIKZF3 | |
| SCHEMBL17362473 | 0.89 | ALDH1A1 (0.45) | ALDH1A1TSHRDDB1CRBNIKZF3 | |
| SCHEMBL29799384 | 0.89 | ALDH1A1 (0.45) | ALDH1A1TSHRDDB1CRBNIKZF3 | |
| SCHEMBL633891 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TSHRDDB1CRBNIKZF3 | |
| SCHEMBL20877507 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TSHRDDB1CRBNIKZF3 | |
| SCHEMBL30693382 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TSHRDDB1CRBNIKZF3 | |
| SCHEMBL8477142 | 0.82 | ALDH1A1 (0.49) | ALDH1A1TSHRDDB1CRBNIKZF3 | |
| SCHEMBL2665681 | 0.80 | L3MBTL1 (0.54) | ALDH1A1TSHRDDB1CRBNIKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4048677-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | Arkuda Therapeutics (US) | 2022-08-31 | — | — | EP | disclosed |
| CN-114044800-A | Aryl, heteroaryl and heterocyclic compounds for the treatment of medical disorders | 艾其林医药公司 | 2022-02-15 | — | — | CN | disclosed |