Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 13/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22126597 | 1.00 | USP30 (0.58) | USP30ABCB1SCD5GPR119CKS1B | |
| SCHEMBL22126595 | 1.00 | USP30 (0.58) | USP30ABCB1SCD5GPR119CKS1B | |
| SCHEMBL22126589 | 0.84 | NAMPT (0.40) | USP30GPR119 | |
| SCHEMBL31200501 | 0.84 | NAMPT (0.40) | USP30 | |
| SCHEMBL20031592 | 0.84 | NAMPT (0.40) | USP30GPR119 | |
| SCHEMBL20031590 | 0.83 | USP30 (0.67) | USP30GPR119 | |
| SCHEMBL31200641 | 0.82 | NLRP3 (0.44) | USP30GPR119 | |
| SCHEMBL31200656 | 0.80 | IL1B (0.42) | — | |
| SCHEMBL22126591 | 0.78 | NAMPT (0.41) | USP30 | |
| SCHEMBL20031443 | 0.78 | NAMPT (0.41) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790169-B | Cyanopyrrolidine derivatives having activity as USP30 inhibitors | 特殊治疗有限公司 | 2022-03-29 | — | — | CN | disclosed |