Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.69 |
| ▸ | GLP1R | P43220 | 5/20 | 0.64 |
| ▸ | NPY1R | P25929 | 1/20 | 0.63 |
| ▸ | NPY2R | P49146 | 1/20 | 0.63 |
| ▸ | NPY4R | P50391 | 1/20 | 0.63 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.63 |
| ▸ | MC4R | P32245 | 1/20 | 0.63 |
| ▸ | MC5R | P33032 | 1/20 | 0.63 |
| ▸ | MC3R | P41968 | 1/20 | 0.63 |
| ▸ | MC1R | Q01726 | 1/20 | 0.63 |
| ▸ | PTH1R | Q03431 | 6/20 | 0.63 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.62 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30006939 | 0.99 | KEAP1 (0.70) | KEAP1GLP1RNPY1RNPY2RNPY4R | |
| SCHEMBL30775451 | 0.96 | MC4R (0.67) | KEAP1GLP1RNPY1RNPY2RNPY4R | |
| SCHEMBL30775448 | 0.94 | IL23R (0.68) | KEAP1GLP1RMC4RMC5RMC3R | |
| SCHEMBL30887976 | 0.94 | KEAP1 (0.69) | KEAP1GLP1RMC4RMC5RMC3R | |
| SCHEMBL30495698 | 0.92 | GLP1R (0.66) | KEAP1GLP1RNPY1RNPY2RNPY4R | |
| SCHEMBL30432613 | 0.92 | NPY1R (0.69) | KEAP1GLP1RNPY1RNPY2RNPY4R | |
| SCHEMBL30658214 | 0.91 | NPY2R (0.72) | GLP1RNPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL30932069 | 0.91 | GLP1R (0.74) | KEAP1GLP1RNPY1RNPY2RNPY4R | |
| SCHEMBL31694497 | 0.91 | CXCR4 (0.64) | KEAP1NPY1RNPY2RNPY4RNPY5R | |
| Dynorphin A (1-17) SCHEMBL31331988 | 0.91 | NPY1R (0.68) | KEAP1GLP1RNPY1RNPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250312463-A1 | AUGMENTED PEPTIDE COMPOSITIONS AND METHODS | Neo7Bioscience, Inc. (US) | 2025-10-09 | — | — | US | claimed |
| US-12372538-B2 | Exosome assay for depression and psychosis and methods and agents for treating depression, psychosis and schizophrenia | GOETZL EDWARD J (US) | 2025-07-29 | — | — | US | claimed |
| CN-120053690-A | Lipid nanoparticle-coated MOTS-c peptide and derivative thereof | 江苏省人民医院（南京医科大学第一附属医院） | 2025-05-30 | — | — | CN | claimed |
| CN-119746031-A | Use of MOTS-c polypeptides and analogs thereof to reverse tumor cell TRAIL resistance by activating MEF2A pathway | 吉林医药学院 | 2025-04-04 | — | — | CN | claimed |
| CN-119746030-A | Application of MOTS-c polypeptide and analogue thereof in preparation of medicines for preventing and/or treating tumors or cancers | 吉林医药学院 | 2025-04-04 | — | — | CN | claimed |
| CN-119752913-A | MOTS-c targeting nucleic acid aptamer and application thereof | 中山大学孙逸仙纪念医院 | 2025-04-04 | — | — | CN | claimed |
| CN-119241659-A | Use of MOTS-c and amino acid mutant polypeptides thereof in wound healing | 西北大学 | 2025-01-03 | — | — | CN | claimed |
| CN-118831150-A | Application of MOTS-c peptide and derivatives thereof in preparation of medicines for treating fetal abortion caused by intrahepatic cholestasis in gestation period | 江南大学 | 2024-10-25 | — | — | CN | claimed |
| EP-4444870-A1 | METHODS AND COMPOSITIONS FOR GENERATING HUMAN ERYTHROID PROGENITOR CELLS | Trailhead Biosystems Inc. (US) | 2024-10-16 | — | — | EP | claimed |
| CN-118750576-A | Application of active peptide composition in preparation of medicines for promoting proliferation of umbilical cord hematopoietic stem cells | 北京易优联科技有限公司 | 2024-10-11 | — | — | CN | claimed |
| US-11737999-B2 | Amino acid compositions and methods for the treatment of post-acute sequelae of COVID-19 | AXCELLA HEALTH INC. (US) | 2023-08-29 | — | — | US | claimed |
| CN-116474073-A | Application of MOTS-c peptide and derivatives thereof in preparation of intrauterine growth restriction treatment drugs | 江南大学 | 2023-07-25 | — | — | CN | claimed |
| US-20230228767-A1 | DETECTION OF SARS-COV-2 PROTEINS AND MITOCHONDRIAL PROTEINS IN PLASMA NEURON-DERIVED EXTRACELLULAR VESICLES AND ASTROCYTE-DERIVED EXTRACELLULAR VESICLES | GOETZL EDWARD J (US) | 2023-07-20 | — | — | US | claimed |
| WO-2023107477-A1 | METHODS AND COMPOSITIONS FOR GENERATING HUMAN ERYTHROID PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. (US) | 2023-06-15 | — | — | WO | claimed |
| US-20230174938-A1 | METHODS AND COMPOSITIONS FOR GENERATING HUMAN ERYTHROID PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. | 2023-06-08 | — | — | US | claimed |
| CN-115919999-A | Application of MOTS-c in preparation of medicine for relieving and treating neuropathic pain | 徐州医科大学 | 2023-04-07 | — | — | CN | claimed |
| US-20230038163-A1 | AMINO ACID COMPOSITIONS AND METHODS FOR THE TREATMENT OF POST-ACUTE SEQUELAE OF COVID-19 | AXCELLA (ASSIGNMENT FOR THE BENEFIT OF CREDITORS), LLC | 2023-02-09 | — | — | US | claimed |
| WO-2023009444-A1 | AMINO ACID COMPOSITIONS AND METHODS FOR USE IN THE TREATMENT OF POST-ACUTE SEQUELAE OF COVID-19 | AXCELLA HEALTH INC. (US) | 2023-02-02 | — | — | WO | claimed |
| CN-115444926-A | Application of MOTS-c peptide and derivative thereof in preparation of medicine for treating radioactive lung injury | 江南大学 | 2022-12-09 | — | — | CN | claimed |
| US-20220128575-A1 | EXOSOME ASSAY FOR DEPRESSION AND PSYCHOSIS AND METHODS AND AGENTS FOR TREATING DEPRESSION, PSYCHOSIS AND SCHIZOPHRENIA | GOETZL EDWARD J (US) | 2022-04-28 | — | — | US | claimed |