Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.70 |
| ▸ | GLP1R | P43220 | 5/20 | 0.64 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.63 |
| ▸ | NPY1R | P25929 | 1/20 | 0.63 |
| ▸ | NPY2R | P49146 | 1/20 | 0.63 |
| ▸ | NPY4R | P50391 | 1/20 | 0.63 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.63 |
| ▸ | MC4R | P32245 | 1/20 | 0.63 |
| ▸ | MC5R | P33032 | 1/20 | 0.63 |
| ▸ | MC3R | P41968 | 1/20 | 0.63 |
| ▸ | MC1R | Q01726 | 1/20 | 0.63 |
| ▸ | PTH1R | Q03431 | 6/20 | 0.63 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29545955 | 0.99 | KEAP1 (0.69) | KEAP1GLP1RC5AR1NPY1RNPY2R | |
| SCHEMBL30775451 | 0.96 | MC4R (0.67) | KEAP1GLP1RNPY1RNPY2RNPY4R | |
| SCHEMBL30887976 | 0.95 | KEAP1 (0.69) | KEAP1GLP1RMC4RMC5RMC3R | |
| SCHEMBL30775448 | 0.94 | IL23R (0.68) | KEAP1GLP1RMC4RMC5RMC3R | |
| SCHEMBL30495698 | 0.92 | GLP1R (0.66) | KEAP1GLP1RNPY1RNPY2RNPY4R | |
| SCHEMBL30432613 | 0.92 | NPY1R (0.69) | KEAP1GLP1RC5AR1NPY1RNPY2R | |
| SCHEMBL30932069 | 0.91 | GLP1R (0.74) | KEAP1GLP1RNPY1RNPY2RNPY4R | |
| SCHEMBL30658214 | 0.91 | NPY2R (0.72) | GLP1RNPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL30432809 | 0.91 | GLP1R (0.68) | KEAP1GLP1RC5AR1NPY1RNPY2R | |
| SCHEMBL31694492 | 0.91 | KEAP1 (0.70) | KEAP1GLP1RNPY1RNPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118236470-A | Application of MOTS-c peptide and derivatives thereof in preparation of bronchial asthma treatment drugs | 无锡市第二人民医院 | 2024-06-25 | — | — | CN | disclosed |
| CN-117919374-A | Application of MOTS-c polypeptide in preparation of medicines for preventing lung ischemia reperfusion vascular endothelial cell injury | 无锡市人民医院 | 2024-04-26 | — | — | CN | disclosed |
| CN-117085110-A | Application of MOTS-c polypeptide in preparation of medicines for preventing and/or treating bronchopulmonary dysplasia | 江南大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-117064999-A | Application of MOTS-c peptide, derivatives and chimeric thereof in preparation of anti-fatigue composition | 军事科学院军事医学研究院环境医学与作业医学研究所 | 2023-11-17 | — | — | CN | disclosed |
| CN-116474073-A | Application of MOTS-c peptide and derivatives thereof in preparation of intrauterine growth restriction treatment drugs | 江南大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-115444926-A | Application of MOTS-c peptide and derivative thereof in preparation of medicine for treating radioactive lung injury | 江南大学 | 2022-12-09 | — | — | CN | disclosed |