SCHEMBL30775451

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(=N)N)NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	MC4R	P32245	2/20	0.67

▸	MC5R	P33032	2/20	0.67

▸	MC3R	P41968	2/20	0.67

▸	MC1R	Q01726	2/20	0.67

▸	KEAP1	Q14145	1/20	0.65

▸	IL23R	Q5VWK5	4/20	0.65

▸	GLP1R	P43220	3/20	0.64

▸	CXCL8	P10145	1/20	0.63

▸	NPY1R	P25929	1/20	0.63

▸	NPY2R	P49146	1/20	0.63

▸	NPY4R	P50391	1/20	0.63

▸	NPY5R	Q15761	1/20	0.63

▸	RXFP1	Q9HBX9	1/20	0.62

▸	PTH1R	Q03431	5/20	0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30775448	0.98	IL23R (0.68)	MC4RMC5RMC3RMC1RKEAP1
SCHEMBL30006939	0.96	KEAP1 (0.70)	MC4RMC5RMC3RMC1RKEAP1
SCHEMBL29545955	0.96	KEAP1 (0.69)	MC4RMC5RMC3RMC1RKEAP1
SCHEMBL30495698	0.91	GLP1R (0.66)	KEAP1GLP1RNPY1RNPY2RNPY4R
SCHEMBL30887976	0.91	KEAP1 (0.69)	MC4RMC5RMC3RMC1RKEAP1
Dynorphin A (1-17) SCHEMBL30248363	0.90	NPY1R (0.68)	KEAP1IL23RGLP1RNPY1RNPY2R
Dynorphin A (1-17) SCHEMBL31331988	0.90	NPY1R (0.68)	KEAP1IL23RGLP1RNPY1RNPY2R
SCHEMBL30432613	0.90	NPY1R (0.69)	MC4RMC5RMC3RMC1RKEAP1
SCHEMBL29361885	0.89	GLP1R (0.66)	MC4RMC5RMC3RMC1RKEAP1
SCHEMBL29874649	0.89	MC4R (0.69)	MC4RMC5RMC3RMC1RIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-117582378-A	Peptide compositions for protecting and maintaining mitochondria and their functions	主流源生物科技(上海)有限公司	2024-02-23	—	—	CN	disclosed