Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28371859 | 1.00 | GPR119 (0.46) | GPR119RIPK1KDM4EBLMALOX15 | |
| SCHEMBL28441614 | 0.86 | PARP1 (0.43) | GPR119ALDH1A1 | |
| SCHEMBL26115692 | 0.86 | PARP1 (0.43) | GPR119RIPK1ALDH1A1 | |
| SCHEMBL22285173 | 0.86 | NR1H2 (0.49) | GPR119RIPK1 | |
| SCHEMBL4325057 | 0.86 | NR1H2 (0.49) | GPR119RIPK1 | |
| SCHEMBL874416 | 0.86 | NR1H2 (0.49) | GPR119RIPK1 | |
| SCHEMBL30675171 | 0.84 | GPR119 (0.53) | GPR119RIPK1KDM4EBLMALOX15 | |
| SCHEMBL27703992 | 0.84 | GPR119 (0.53) | GPR119RIPK1KDM4EBLMALOX15 | |
| SCHEMBL23992271 | 0.83 | ALDH1A1 (0.56) | GPR119RIPK1KDM4EBLMALOX15 | |
| SCHEMBL24114777 | 0.83 | ALDH1A1 (0.56) | GPR119RIPK1KDM4EBLMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424201-B | Protein kinase inhibitors that promote liver regeneration or reduce or prevent hepatocyte death | 海帕瑞吉尼克斯股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117561253-A | Compounds and compositions for treating disorders related to STING activity | 艾福姆德尤股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-111819176-B | 4-azaindole compounds | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-111699185-B | 6-azaindole compounds | 百时美施贵宝公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-109843885-B | Medicinal salt of antineoplastic heterocyclic imidazole compound | 上海汇伦生物科技有限公司 | 2022-03-29 | — | — | CN | disclosed |