Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 5/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22906900 | 1.00 | CTSL (0.40) | CTSLCTSBCTSKACACBMAOB | |
| SCHEMBL22906969 | 1.00 | CTSL (0.40) | CTSLCTSBCTSKACACBMAOB | |
| SCHEMBL20129070 | 0.80 | ACACB (0.37) | CTSLCTSBCTSKACACBMAOB | |
| SCHEMBL26600712 | 0.76 | ACACB (0.41) | ACACB | |
| SCHEMBL22906837 | 0.75 | CYP11B2 (0.41) | ACACBCNR1CYP11B2NAAARET | |
| SCHEMBL20120315 | 0.74 | OPRK1 (0.41) | CTSLCTSBCTSKACACBSLC6A4 | |
| SCHEMBL20120314 | 0.74 | OPRK1 (0.41) | CTSLCTSBCTSKACACBSLC6A4 | |
| SCHEMBL21877007 | 0.74 | SLC6A4 (0.35) | SLC6A4 | |
| SCHEMBL29547656 | 0.73 | ACACB (0.39) | CTSLCTSBCTSKACACBNAAA | |
| SCHEMBL27139547 | 0.73 | ACACB (0.39) | CTSLCTSBCTSKACACBNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954801-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114867727-B | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-114867727-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| EP-3999182-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |