Saccharin

Saccharin

SCHEMBL2954783

O=C1[N-]S(=O)(=O)c2ccccc21.O=C1[N-]S(=O)(=O)c2ccccc21.[Fe+2]

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.44
CA9 Q16790 5/20 0.41
CA12 O43570 5/20 0.41
KMT2A Q03164 3/20 0.41
CA2 P00918 2/20 0.41
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
CA1 P00915 1/20 0.41
LMNA P02545 1/20 0.41
BCHE P06276 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
ELANE P08246 2/20 0.36
MEN1 O00255 2/20 0.35
CDC25B P30305 1/20 0.35
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Saccharin SCHEMBL953945 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2
Saccharin SCHEMBL49027 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2
Saccharin SCHEMBL3372 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2
Saccharin SCHEMBL10618576 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2
Saccharin SCHEMBL10399957 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2
Saccharin SCHEMBL787894 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2
Saccharin SCHEMBL8668442 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2
Saccharin SCHEMBL5870938 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2
Saccharin SCHEMBL473608 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2
Saccharin SCHEMBL176171 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4392045-A1 IRON COMPOSITIONS AND METHODS OF MAKING AND USING THEM American Regent, Inc. (US) 2024-07-03 EP claimed
WO-2023028252-A1 IRON COMPOSITIONS AND METHODS OF MAKING AND USING THEM AMERICAN REGENT, INC. (US) 2023-03-02 WO claimed
EP-1973549-A2 METHODS AND COMPOSITIONS FOR ADMINISTRATION OF IRON Luitpold Pharmaceuticals, Inc. (US) 2008-10-01 EP claimed
WO-2007081744-A2 METHODS AND COMPOSITIONS FOR ADMINISTRATION OF IRON LUITPOLD PHARMACEUTICALS, INC. (US) 2007-07-19 WO claimed
US-20070161600-A1 complexed with iron; bioavailability; anemia LUITPOLD PHARMACEUTICALS, INC. (US) 2007-07-12 US claimed
EP-4392045-A1 IRON COMPOSITIONS AND METHODS OF MAKING AND USING THEM American Regent, Inc. (US) 2024-07-03 EP disclosed
CN-118103047-A Iron compositions and methods of making and using the same 美国瑞根特有限公司 2024-05-28 CN disclosed
US-20230084291-A1 IRON COMPOSITIONS AND METHODS OF MAKING AND USING THEM AMERICAN REGENT, INC. (US) 2023-03-16 US disclosed
WO-2023028252-A1 IRON COMPOSITIONS AND METHODS OF MAKING AND USING THEM AMERICAN REGENT, INC. (US) 2023-03-02 WO disclosed
US-20230008240-A1 METHODS AND COMPOSITIONS FOR ADMINISTRATION OF IRON AMERICAN REGENT, INC. (US) 2023-01-12 US disclosed
US-11364260-B2 Methods and compositions for administration of iron AMERICAN REGENT, INC. (US) 2022-06-21 US disclosed
US-11344568-B2 Methods and compositions for administration of iron AMERICAN REGENT, INC. (US) 2022-05-31 US disclosed
EP-1973549-A2 METHODS AND COMPOSITIONS FOR ADMINISTRATION OF IRON Luitpold Pharmaceuticals, Inc. (US) 2008-10-01 EP disclosed
WO-2008070703-A1 APPARATUS AND METHOD FOR ISOLATING IRON COMPONENTS FROM SERUM BAXTER INTERNATIONAL INC. (US) 2008-06-12 WO disclosed
US-20080132465-A1 APPARATUS AND METHOD FOR ISOLATING IRON COMPONENTS FROM SERUM BAXTER INTERNATIONAL INC. 2008-06-05 US disclosed
WO-2007081744-A2 METHODS AND COMPOSITIONS FOR ADMINISTRATION OF IRON LUITPOLD PHARMACEUTICALS, INC. (US) 2007-07-19 WO disclosed
US-20070161600-A1 complexed with iron; bioavailability; anemia LUITPOLD PHARMACEUTICALS, INC. (US) 2007-07-12 US disclosed
US-20050053696-A1 Stable and bioavailable iron fortified beverages KRAFT FOOD HOLDINGS, INC. 2005-03-10 US disclosed
WO-2003013283-A1 STABLE AND BIOAVAILABLE IRON FORTIFIED BEVERAGES KRAFT FOODS HOLDINGS, INC. (US) 2003-02-20 WO disclosed
US-20030031757-A1 Stable and bioavailable iron fortified beverages KRAFT FOOD HOLDINGS, INC. 2003-02-13 US disclosed