Saccharin

Saccharin

SCHEMBL953945

O=C1[N-]S(=O)(=O)c2ccccc21.O=C1[N-]S(=O)(=O)c2ccccc21.O=C1[N-]S(=O)(=O)c2ccccc21.O=C1[N-]S(=O)(=O)c2ccccc21.[C+4]

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.44
CA9 Q16790 5/20 0.41
CA12 O43570 5/20 0.41
KMT2A Q03164 3/20 0.41
CA2 P00918 2/20 0.41
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
CA1 P00915 1/20 0.41
LMNA P02545 1/20 0.41
BCHE P06276 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
ELANE P08246 2/20 0.36
MEN1 O00255 2/20 0.35
CDC25B P30305 1/20 0.35
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Saccharin SCHEMBL49027 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2
Saccharin SCHEMBL8668442 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2
Saccharin SCHEMBL3372 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2
Saccharin SCHEMBL10618576 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2
Saccharin SCHEMBL5870938 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2
Saccharin SCHEMBL787894 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2
Saccharin SCHEMBL10399957 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2
Saccharin SCHEMBL2954783 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2
Saccharin SCHEMBL473608 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2
Saccharin SCHEMBL176171 0.96 GPR3 (0.44) GPR3CA9CA12KMT2ACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10584445-B2 Functionalizing cellulosic and lignocellulosic materials XYLECO, INC. (US) 2020-03-10 US claimed
US-20190218721-A1 FUNCTIONALIZING CELLULOSIC AND LIGNOCELLULOSIC MATERIALS XYLECO, INC. 2019-07-18 US claimed
EP-3480217-A1 PROCESSING BIOMASS Xyleco, Inc. (US) 2019-05-08 EP claimed
US-20160333528-A1 FUNCTIONALIZING CELLULOSIC AND LIGNOCELLULOSIC MATERIALS XYLECO, INC. 2016-11-17 US claimed
CN-105733694-A Biomass recycling and recovering equipment 青岛清泉生物科技有限公司 2016-07-06 CN claimed
EP-2963060-A2 PROCESSING BIOMASS Xyleco, Inc. (US) 2016-01-06 EP claimed
US-9175443-B2 Functionalizing cellulosic and lignocellulosic materials XYLECO, INC. (US) 2015-11-03 US claimed
US-20150225902-A1 FUNCTIONALIZING CELLULOSIC AND LIGNOCELLULOSIC MATERIALS XYLECO, INC. 2015-08-13 US claimed
US-8063201-B2 Carbohydrates XYLECO, INC. (US) 2011-11-22 US claimed
US-8052838-B2 Functionalizing cellulosic and lignocellulosic materials XYLECO, INC. (US) 2011-11-08 US claimed
US-20110067830-A1 FUNCTIONALIZING CELLULOSIC AND LIGNOCELLULOSIC MATERIALS XYLECO, INC (US) 2011-03-24 US claimed
US-20110065910-A1 CARBOHYDRATES XYLECO, INC (US) 2011-03-17 US claimed
EP-2276795-A2 PROCESSING BIOMASS Xyleco, Inc. (US) 2011-01-26 EP claimed
US-7867359-B2 Functionalizing cellulosic and lignocellulosic materials XYLECO, INC. (US) 2011-01-11 US claimed
US-20100124583-A1 PROCESSING BIOMASS XYLECO, INC. (US) 2010-05-20 US claimed
US-20090312537-A1 CARBOHYDRATES XYLECO, INC. (US) 2009-12-17 US claimed
US-20090283229-A1 FUNCTIONALIZING CELLULOSIC AND LIGNOCELLULOSIC MATERIALS XYLECO, INC. (US) 2009-11-19 US claimed
WO-2009134746-A1 CARBOHYDRATES XYLECO, INC. (US) 2009-11-05 WO claimed
WO-2009134736-A2 FUNCTIONALIZING CELLULOSIC AND LIGNOCELLULOSIC MATERIALS XYLECO, INC. (US) 2009-11-05 WO claimed
WO-2009134791-A2 PROCESSING BIOMASS XYLECO, INC. (US) 2009-11-05 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100124583-A1 PROCESSING BIOMASS FIP1L1, MANBA, BCAT2 GPR3 2943/4885CA9 3497/4885CA12 4653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.