Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19642415 | 1.00 | MAOA (0.40) | MAOAUSP30CHRNA7KCNH2HTR1A | |
| SCHEMBL19642382 | 1.00 | MAOA (0.40) | MAOAUSP30CHRNA7KCNH2HTR1A | |
| SCHEMBL19642429 | 0.84 | HSD11B1 (0.40) | MAOAKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL29547630 | 0.84 | HSD11B1 (0.40) | MAOAKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL19642412 | 0.84 | KHK (0.40) | MAOACHRNA7KCNH2HTR1AHTR7 | |
| SCHEMBL19642414 | 0.84 | KHK (0.40) | MAOACHRNA7KCNH2HTR1AHTR7 | |
| SCHEMBL19642317 | 0.84 | LOXL2 (0.45) | MAOACHRNA7KCNH2 | |
| SCHEMBL19642244 | 0.84 | LOXL2 (0.45) | MAOACHRNA7KCNH2 | |
| SCHEMBL19662153 | 0.84 | KHK (0.40) | MAOACHRNA7KCNH2HTR1AHTR7 | |
| SCHEMBL19662373 | 0.84 | MAOA (0.38) | MAOACHRNA7KCNH2HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311860-B | Xanthone derivatives for the treatment or prevention of hepatitis B virus diseases | 豪夫迈·罗氏有限公司 | 2022-04-08 | — | — | CN | claimed |
| CN-109311860-B | Xanthone derivatives for the treatment or prevention of hepatitis B virus diseases | 豪夫迈·罗氏有限公司 | 2022-04-08 | — | — | CN | disclosed |