SCHEMBL29548460

SCHEMBL29548460

CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(C)C

nearest known ligand 0.71

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 20/20 0.71
▸ ECE1 P42892 1/20 0.66
▸ MUS81 Q96NY9 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30691823 1.00 GLP1R (0.71) GLP1RECE1MUS81
SCHEMBL30658231 0.92 GLP1R (0.70) GLP1RECE1MUS81
SCHEMBL30887554 0.90 C5AR1 (0.66) GLP1RECE1MUS81
SCHEMBL29942605 0.90 GLP1R (0.84) GLP1R
SCHEMBL28662518 0.90 GLP1R (0.84) GLP1R
SCHEMBL31099271 0.90 GLP1R (0.84) GLP1R
SCHEMBL29431871 0.90 GLP1R (0.84) GLP1R
SCHEMBL29801807 0.90 GLP1R (0.84) GLP1R
SCHEMBL30607448 0.89 GLP1R (0.67) GLP1R
SCHEMBL29604164 0.89 C5AR1 (0.65) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230135945-A1 Method for Measuring Modulation in the Activity of a G Protein-Coupled Receptor CISBIO ASSAYS (FR) 2023-05-04 — — US claimed
US-20220099669-A1 METHOD FOR MEASURING THE MODULATION OF THE ACTIVATION OF A G PROTEIN-COUPLED RECEPTOR WITH GTP ANALOGUES CISBIO BIOASSAYS (FR) 2022-03-31 — — US claimed
US-12584916-B2 Method for measuring the modulation of the activation of a G protein-coupled receptor with GTP analogues CISBIO BIOASSAYS (FR) 2026-03-24 — — US disclosed
US-20230135945-A1 Method for Measuring Modulation in the Activity of a G Protein-Coupled Receptor CISBIO ASSAYS (FR) 2023-05-04 — — US disclosed
US-20220099669-A1 METHOD FOR MEASURING THE MODULATION OF THE ACTIVATION OF A G PROTEIN-COUPLED RECEPTOR WITH GTP ANALOGUES CISBIO BIOASSAYS (FR) 2022-03-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584916-B2 Method for measuring the modulation of the activation of a G protein-coupled receptor with GTP analogues GNAI1, GNAI3, GNB1 GLP1R 156/4885ECE1 3130/4885MUS81 4290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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