Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.34 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.34 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.31 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29548173 | 0.84 | PDE10A (0.34) | PDE10A | |
| SCHEMBL29548852 | 0.84 | CAMKK1 (0.34) | PDE10ACAMKK1CAMKK2 | |
| SCHEMBL29548522 | 0.79 | ALDH1A1 (0.33) | PDE10ACAMKK1CAMKK2 | |
| SCHEMBL29548569 | 0.72 | GRIN1 (0.50) | PDE10AEPHB3 | |
| SCHEMBL29548217 | 0.72 | ALDH1A1 (0.40) | PDE10ACAMKK1CAMKK2 | |
| SCHEMBL29548244 | 0.70 | ALDH1A1 (0.34) | PDE10ACAMKK1CAMKK2 | |
| SCHEMBL24338888 | 0.66 | CSNK2A1 (0.34) | CAMKK1CAMKK2PIK3CBPRKDCATM | |
| SCHEMBL29548138 | 0.66 | CAMKK1 (0.34) | CAMKK1CAMKK2 | |
| SCHEMBL29548310 | 0.65 | DRD2 (0.39) | CAMKK1CAMKK2 | |
| SCHEMBL29549132 | 0.63 | CAMKK1 (0.35) | CAMKK1CAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070288-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND | 旭化成ファーマ株式会社 | 2022-04-07 | — | — | WO | disclosed |