Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.38 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29548244 | 0.89 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1CAMKK1CAMKK2TSHR | |
| SCHEMBL29548522 | 0.80 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1CAMKK1CAMKK2TSHR | |
| SCHEMBL29548203 | 0.78 | CAMKK1 (0.38) | ALDH1A1CAMKK1CAMKK2DRD4DRD3 | |
| SCHEMBL29548852 | 0.76 | CAMKK1 (0.34) | CAMKK1CAMKK2PDE10A | |
| SCHEMBL29548569 | 0.76 | GRIN1 (0.50) | ALDH1A1NPSR1PDE10A | |
| SCHEMBL29549122 | 0.75 | CAMKK1 (0.38) | ALDH1A1CAMKK1CAMKK2DRD4DRD3 | |
| SCHEMBL27266235 | 0.73 | PDE10A (0.39) | ALDH1A1L3MBTL1PDE10A | |
| SCHEMBL12540412 | 0.73 | CAMKK1 (0.41) | ALDH1A1CAMKK1CAMKK2TSHRPDE10A | |
| SCHEMBL29549126 | 0.72 | PDE10A (0.34) | CAMKK1CAMKK2PDE10A | |
| SCHEMBL29548929 | 0.69 | DRD4 (0.39) | ALDH1A1CAMKK1CAMKK2TSHRDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070288-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND | 旭化成ファーマ株式会社 | 2022-04-07 | — | — | WO | disclosed |