SCHEMBL29548698

SCHEMBL29548698

N=C(N)NCCC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 6/20 0.55
▸ OPRD1 P41143 6/20 0.55
▸ NPFFR1 Q9GZQ6 2/20 0.55
▸ NPFFR2 Q9Y5X5 2/20 0.55
▸ NMUR2 Q9GZQ4 2/20 0.53
▸ NMUR1 Q9HB89 2/20 0.53
▸ F2 P00734 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31676699 0.96 OPRM1 (0.57) OPRM1OPRD1NPFFR1NPFFR2
SCHEMBL31676697 0.93 OPRM1 (0.59) OPRM1OPRD1NPFFR1NPFFR2
SCHEMBL30233902 0.92 OPRM1 (0.62) OPRM1OPRD1NPFFR1NPFFR2NMUR2
SCHEMBL32664435 0.91 NTSR2 (0.58) OPRM1OPRD1NPFFR1NPFFR2
SCHEMBL30402818 0.90 NMUR2 (0.66) OPRM1OPRD1NMUR2NMUR1
SCHEMBL29531543 0.90 OPRD1 (0.55) OPRM1OPRD1NPFFR1NPFFR2
SCHEMBL31187483 0.88 NMUR2 (0.63) OPRM1OPRD1NMUR2NMUR1
SCHEMBL31316687 0.88 OPRM1 (0.63) OPRM1OPRD1
SCHEMBL31410880 0.88 OPRM1 (0.58) OPRM1OPRD1NPFFR1NPFFR2NMUR2
SCHEMBL30695568 0.88 OPRM1 (0.56) OPRM1OPRD1NPFFR1NPFFR2NMUR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110088119-B Peptides having anticancer activity, and pharmaceutical composition, health functional food composition and functional cosmetic composition containing the same as active ingredient 汉阳大学校产学协力团 2023-08-18 — — CN claimed
US-12605453-B2 CP2C-targeting peptide-based anticancer agent INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2026-04-21 — — US disclosed
CN-110088119-B Peptides having anticancer activity, and pharmaceutical composition, health functional food composition and functional cosmetic composition containing the same as active ingredient 汉阳大学校产学协力团 2023-08-18 — — CN disclosed
CN-110088119-B Peptides having anticancer activity, and pharmaceutical composition, health functional food composition and functional cosmetic composition containing the same as active ingredient 汉阳大学校产学协力团 2023-08-18 — — CN disclosed
US-20230078718-A1 UNSATURATED FATTY ACID-CONJUGATED CP2C-TARGETING PEPTIDE-BASED ANTICANCER AGENT INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2023-03-16 — — US disclosed
EP-4101470-A1 UNSATURATED FATTY ACID-CONJUGATED CP2C-TARGETING PEPTIDE-BASED ANTICANCER AGENT Industry-University Cooperation Foundation Hanyang University (KR) 2022-12-14 — — EP disclosed
CN-115361975-A Anticancer agent based on unsaturated fatty acid conjugated CP2C targeting peptide 汉阳大学校产学协力团 2022-11-18 — — CN disclosed
EP-4005583-A1 CP2C-TARGETING PEPTIDE-BASED ANTICANCER AGENT Industry - University Cooperation Foundation Hanyang University (KR) 2022-06-01 — — EP disclosed
US-20220160888-A1 CP2C-TARGETING PEPTIDE-BASED ANTICANCER AGENT INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2022-05-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220160888-A1 CP2C-TARGETING PEPTIDE-BASED ANTICANCER AGENT SREBF2, BCLAF1, CIP2A OPRM1 4060/4885OPRD1 4157/4885NPFFR1 1114/4885
US-20230078718-A1 UNSATURATED FATTY ACID-CONJUGATED CP2C-TARGETING PEPTIDE-BASED ANTICANCER AGENT ZDHHC2, FFAR2, SLC27A2 OPRM1 4383/4885OPRD1 4413/4885NPFFR1 345/4885
US-12605453-B2 CP2C-targeting peptide-based anticancer agent SREBF2, SLC27A2, ZDHHC2 OPRM1 3263/4885OPRD1 3318/4885NPFFR1 1015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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