Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 3/20 | 0.60 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.60 |
| ▸ | CDK2 | P24941 | 3/20 | 0.60 |
| ▸ | CDK9 | P50750 | 3/20 | 0.60 |
| ▸ | GSK3B | P49841 | 7/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.58 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.58 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.58 |
| ▸ | CLK1 | P49759 | 3/20 | 0.58 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.58 |
| ▸ | CDC7 | O00311 | 1/20 | 0.55 |
| ▸ | PRKACA | P17612 | 2/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.53 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.53 |
| ▸ | NFATC1 | O95644 | 2/20 | 0.49 |
| ▸ | F12 | P00748 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738230 | 1.00 | CCNT1 (0.60) | CCNT1CCNA2CDK2CDK9GSK3B | |
| Hydrochloric Acid SCHEMBL5748840 | 0.98 | CCNT1 (0.59) | CCNT1CCNA2CDK2CDK9GSK3B | |
| SCHEMBL15901800 | 0.81 | HTR2C (0.49) | CCNT1CCNA2CDK2CDK9GSK3B | |
| SCHEMBL1914955 | 0.80 | HSP90AA1 (0.59) | CCNT1CCNA2CDK2CDK9GSK3B | |
| SCHEMBL30046927 | 0.79 | HSP90AA1 (0.60) | CCNT1CCNA2CDK2CDK9GSK3B | |
| SCHEMBL18130895 | 0.79 | HSP90AA1 (0.60) | CCNT1CCNA2CDK2CDK9GSK3B | |
| SCHEMBL5747667 | 0.79 | DYRK1A (0.55) | CCNT1CCNA2CDK2CDK9GSK3B | |
| SCHEMBL31452201 | 0.79 | MAPT (0.43) | CCNT1CCNA2CDK2CDK9GSK3B | |
| SCHEMBL17463149 | 0.79 | ALDH1A1 (0.49) | CCNT1CCNA2CDK2CDK9DYRK1A | |
| SCHEMBL5786593 | 0.79 | MAPT (0.43) | CCNT1CCNA2CDK2CDK9GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220267268-A1 | NEW TRICYCLIC 5-HT2 ANTAGONISTS | ANAMAR AB (SE) | 2022-08-25 | — | — | US | disclosed |
| CN-114616224-A | Novel tricyclic 5-HT2Antagonists | 安娜玛有限公司 | 2022-06-10 | — | — | CN | disclosed |
| EP-3986865-A1 | NEW TRICYCLIC 5-HT2 ANTAGONISTS | AnaMar AB (SE) | 2022-04-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267268-A1 | NEW TRICYCLIC 5-HT2 ANTAGONISTS | HTR2B, HTR2C, TPH2 | CCNT1 1016/4885CCNA2 414/4885CDK2 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.