Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 10/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24538202 | 0.94 | MMP2 (0.47) | KMT2AMMP2MCL1NR1H2 | |
| SCHEMBL12166250 | 0.94 | MMP2 (0.47) | KMT2AMMP2MCL1NR1H2 | |
| SCHEMBL2824741 | 0.94 | MMP2 (0.47) | KMT2AMMP2MCL1NR1H2 | |
| SCHEMBL13841901 | 0.94 | MMP2 (0.47) | KMT2AMMP2MCL1NR1H2 | |
| SCHEMBL29548635 | 0.92 | ACE (0.45) | KMT2AMCL1MEN1RAB9AUSP30 | |
| SCHEMBL29549021 | 0.89 | CYP3A4 (0.46) | CYP3A4KMT2AKDM4EMMP2NR1H2 | |
| SCHEMBL21659108 | 0.88 | NPFFR1 (0.45) | CYP3A4KMT2AALDH1A1MMP2MEN1 | |
| SCHEMBL29548385 | 0.87 | MMP2 (0.49) | KDM4EMMP2RAB9ANR1H2 | |
| SCHEMBL4388576 | 0.85 | AGTR2 (0.48) | KMT2AMCL1NR1H2 | |
| SCHEMBL12695279 | 0.84 | MMP2 (0.45) | KMT2AMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230416199-A1 | INHIBITORS OF AMINO ACID TRANSPORT | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-12-28 | — | — | US | disclosed |
| WO-2022087630-A1 | INHIBITORS OF AMINO ACID TRANSPORT | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416199-A1 | INHIBITORS OF AMINO ACID TRANSPORT | SLC1A5, SLC7A1, SLC7A5 | CYP3A4 2946/4885KMT2A 2152/4885KDM4E 4289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.