Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.33 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | PDE1A | P54750 | 1/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29549122 | 0.80 | CAMKK1 (0.38) | DRD4DRD3CAMKK1CAMKK2KDM4E | |
| SCHEMBL24755195 | 0.70 | DRD4 (0.38) | DRD4DRD3KDM4EALDH1A1HSD17B10 | |
| SCHEMBL29548217 | 0.67 | ALDH1A1 (0.40) | DRD4DRD3CAMKK1CAMKK2KDM4E | |
| SCHEMBL29548929 | 0.66 | DRD4 (0.39) | DRD4DRD3CAMKK1CAMKK2KDM4E | |
| SCHEMBL29548203 | 0.65 | CAMKK1 (0.38) | DRD4DRD3CAMKK1CAMKK2KDM4E | |
| SCHEMBL29548356 | 0.65 | PIK3CA (0.32) | CAMKK1CAMKK2 | |
| SCHEMBL12540412 | 0.63 | CAMKK1 (0.41) | DRD4DRD3CAMKK1CAMKK2KDM4E | |
| SCHEMBL29548233 | 0.61 | CAMKK1 (0.36) | DRD4DRD3CAMKK1CAMKK2KDM4E | |
| SCHEMBL13478516 | 0.61 | DRD4 (0.39) | DRD4DRD3KDM4EUSP2ALDH1A1 | |
| SCHEMBL18879064 | 0.58 | EPHB3 (0.50) | DRD4DRD3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070288-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND | 旭化成ファーマ株式会社 | 2022-04-07 | — | — | WO | disclosed |