Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.37 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.37 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | JAK1 | P23458 | 5/20 | 0.37 |
| ▸ | TYK2 | P29597 | 3/20 | 0.37 |
| ▸ | JAK2 | O60674 | 3/20 | 0.36 |
| ▸ | JAK3 | P52333 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29548251 | 0.81 | JAK2 (0.36) | DYRK1ATNK2JAK1TYK2JAK2 | |
| SCHEMBL29548847 | 0.80 | JAK2 (0.35) | TNK2JAK1TYK2JAK2JAK3 | |
| SCHEMBL29548232 | 0.78 | EPHB3 (0.43) | TNK2 | |
| SCHEMBL29548844 | 0.78 | EPHB3 (0.43) | TNK2 | |
| SCHEMBL5849179 | 0.73 | DRD4 (0.39) | DRD4DRD3DYRK1AALDH1A1KDM4E | |
| SCHEMBL29549122 | 0.71 | CAMKK1 (0.38) | DRD4DRD3CAMKK1CAMKK2ALDH1A1 | |
| SCHEMBL29548217 | 0.69 | ALDH1A1 (0.40) | DRD4DRD3CAMKK1CAMKK2ALDH1A1 | |
| SCHEMBL29548203 | 0.69 | CAMKK1 (0.38) | DRD4DRD3CAMKK1CAMKK2ALDH1A1 | |
| SCHEMBL12540412 | 0.67 | CAMKK1 (0.41) | DRD4DRD3CAMKK1CAMKK2ALDH1A1 | |
| SCHEMBL29548839 | 0.66 | DRD4 (0.34) | DRD4DRD3CAMKK1CAMKK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070288-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND | 旭化成ファーマ株式会社 | 2022-04-07 | — | — | WO | disclosed |