Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.36 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 3/20 | 0.32 |
| ▸ | JAK3 | P52333 | 3/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29549132 | 0.79 | CAMKK1 (0.35) | CAMKK1CAMKK2DRD2KCNH2HTR1B | |
| SCHEMBL29548310 | 0.76 | DRD2 (0.39) | CAMKK1CAMKK2DRD2KCNH2HTR1B | |
| SCHEMBL29548852 | 0.74 | CAMKK1 (0.34) | CAMKK1CAMKK2DRD2KCNH2HTR1B | |
| SCHEMBL29548138 | 0.74 | CAMKK1 (0.34) | CAMKK1CAMKK2DRD2KCNH2HTR1B | |
| SCHEMBL29548514 | 0.70 | GPR119 (0.44) | — | |
| SCHEMBL24338888 | 0.67 | CSNK2A1 (0.34) | CAMKK1CAMKK2DRD2 | |
| SCHEMBL29549089 | 0.67 | CAMKK1 (0.32) | CAMKK1CAMKK2KCNH2JAK1JAK3 | |
| SCHEMBL29241277 | 0.64 | CAMKK1 (0.43) | CAMKK1CAMKK2 | |
| SCHEMBL22650905 | 0.63 | PIK3CA (0.47) | CAMKK1CAMKK2JAK1JAK3JAK2 | |
| SCHEMBL30478898 | 0.63 | JAK2 (0.42) | CAMKK1CAMKK2JAK1JAK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070288-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND | 旭化成ファーマ株式会社 | 2022-04-07 | — | — | WO | disclosed |