Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 5/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TPH1 | P17752 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29787412 | 0.87 | PLG (0.48) | PLGEPHX2FFAR4FFAR1MAPT | |
| SCHEMBL29682444 | 0.87 | SLC7A5 (0.49) | PLGFFAR4FFAR1MAPTPOLB | |
| SCHEMBL11664676 | 0.87 | SLC7A5 (0.49) | PLGFFAR4FFAR1MAPTPOLB | |
| SCHEMBL9117821 | 0.87 | SLC7A5 (0.49) | PLGFFAR4FFAR1MAPTPOLB | |
| SCHEMBL7623712 | 0.87 | SLC7A5 (0.49) | PLGFFAR4FFAR1MAPTPOLB | |
| SCHEMBL13613760 | 0.86 | PLG (0.44) | PLGEPHX2FFAR4FFAR1MAPT | |
| SCHEMBL11407678 | 0.81 | PLG (0.51) | PLGFFAR4FFAR1MAPTPOLB | |
| SCHEMBL2152942 | 0.79 | EPHX2 (0.48) | EPHX2MAPTPOLBKMT2ARAB9A | |
| SCHEMBL21510453 | 0.79 | LMNA (0.49) | EPHX2MAPTPOLBKMT2APKM | |
| SCHEMBL2152945 | 0.79 | EPHX2 (0.48) | EPHX2MAPTPOLBKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11285165-B2 | Selective high-affinity polydentate ligands and methods of making such | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2022-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11285165-B2 | Selective high-affinity polydentate ligands and methods of making such | CD44, FCGR3B, FCGR2A | PLG 1155/4885EPHX2 3768/4885FFAR4 4371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.