Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 5/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11664676 | 0.91 | SLC7A5 (0.49) | PLGFFAR4FFAR1PARP10MAPT | |
| SCHEMBL29682444 | 0.91 | SLC7A5 (0.49) | PLGFFAR4FFAR1PARP10MAPT | |
| SCHEMBL7623712 | 0.91 | SLC7A5 (0.49) | PLGFFAR4FFAR1PARP10MAPT | |
| SCHEMBL9117821 | 0.91 | SLC7A5 (0.49) | PLGFFAR4FFAR1PARP10MAPT | |
| SCHEMBL29549311 | 0.87 | PLG (0.48) | PLGFFAR4FFAR1PARP10MAPT | |
| SCHEMBL13613760 | 0.85 | PLG (0.44) | PLGFFAR4FFAR1PARP10MAPT | |
| SCHEMBL30363270 | 0.82 | PLG (0.53) | PLGFFAR4FFAR1PARP10MMP1 | |
| SCHEMBL11407678 | 0.81 | PLG (0.51) | PLGFFAR4FFAR1PARP10MAPT | |
| SCHEMBL29787421 | 0.78 | PLG (0.50) | PLGPTPN1 | |
| SCHEMBL30363157 | 0.77 | PLG (0.49) | PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230120030-A1 | Long-Acting Adrenomedullin Derivatives | UNIVERSITY OF MIYAZAKI (JP) | 2023-04-20 | — | — | US | disclosed |
| US-11414474-B2 | Long-acting adrenomedullin derivatives | UNIVERSITY OF MIYAZAKI (JP) | 2022-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11414474-B2 | Long-acting adrenomedullin derivatives | APLNR, NPBWR1, NPPA | PLG 372/4885FFAR4 1219/4885FFAR1 751/4885 |
| US-20230120030-A1 | Long-Acting Adrenomedullin Derivatives | APLNR, NPBWR1, NPPA | PLG 372/4885FFAR4 1219/4885FFAR1 751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.