SCHEMBL29549434

SCHEMBL29549434

O=c1ccc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 18/20 1.00
HTR1A P08908 5/20 0.77
HTR2A P28223 5/20 0.77
DRD3 P35462 5/20 0.68
DRD4 P21917 4/20 0.68
ADRB2 P07550 2/20 0.68
ADRB1 P08588 2/20 0.68
ADRA2A P08913 2/20 0.68
ADRA2B P18089 2/20 0.68
ADRA2C P18825 2/20 0.68
DRD1 P21728 2/20 0.68
DRD5 P21918 2/20 0.68
SLC6A2 P23975 2/20 0.68
ADRA1D P25100 2/20 0.68
HTR1D P28221 2/20 0.68
HTR1B P28222 2/20 0.68
HTR2C P28335 2/20 0.68
SLC6A4 P31645 2/20 0.68
HTR7 P34969 2/20 0.68
ADRA1A P35348 2/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30552363 1.00 DRD2 (1.00) DRD2HTR1AHTR2ADRD3DRD4
SCHEMBL8423 1.00 DRD2 (1.00) DRD2HTR1AHTR2ADRD3DRD4
Hydrochloric Acid SCHEMBL29365523 0.99 DRD2 (0.98) DRD2HTR1AHTR2ADRD3DRD4
Hydrochloric Acid SCHEMBL29923538 0.99 DRD2 (0.98) DRD2HTR1AHTR2ADRD3DRD4
SCHEMBL30964304 0.99 DRD2 (0.98) DRD2HTR1AHTR2ADRD3DRD4
SCHEMBL14587005 0.97 DRD2 (0.94) DRD2HTR1AHTR2ADRD3DRD4
SCHEMBL251904 0.96 DRD2 (1.00) DRD2HTR1AHTR2ADRD3DRD4
SCHEMBL253673 0.93 DRD2 (1.00) DRD2HTR1AHTR2ADRD3DRD4
SCHEMBL13532797 0.93 DRD2 (0.87) DRD2HTR1AHTR2ADRD3DRD4
SCHEMBL14188956 0.90 DRD2 (0.82) DRD2HTR1AHTR2ADRD3DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4221512-B1 COMPOSITIONS, KITS AND METHODS FOR COLLECTING ANALYTE IN A SALIVA SAMPLE DECIMA DIAGNOSTICS LLC (US) 2025-02-26 EP disclosed
US-20240024310-A1 CARBOSTYRIL DERIVATIVES AND MOOD STABILIZERS FOR TREATING MOOD DISORDERS OTSUKA PHARMA CO LTD (JP) 2024-01-25 US disclosed
US-20230407369-A1 COMPOSITIONS, KITS AND METHODS FOR COLLECTING ANALYTE IN A SALIVA SAMPLE Decima Diagnostics, LLC 2023-12-21 US disclosed
EP-4267138-A1 PRODRUGS OF PHARMACEUTICAL AGENTS Axelyf ehf. (IS) 2023-11-01 EP disclosed
EP-4221512-A1 COMPOSITIONS, KITS AND METHODS FOR COLLECTING ANALYTE IN A SALIVA SAMPLE Decima Diagnostics, LLC (US) 2023-08-09 EP disclosed
CN-111812218-B Method for simultaneously detecting concentration of multiple antipsychotic drugs in serum 南京品生医学检验实验室有限公司 2022-11-18 CN disclosed
US-20220276234-A1 POINT-OF-CARE IMMUNOASSAY FOR QUANTITATIVE SMALL ANALYTE DETECTION Decima Diagnostics, LLC 2022-09-01 US disclosed
WO-2022140705-A1 PRODRUGS OF PHARMACEUTICAL AGENTS ALMARSSON ORN (US) 2022-06-30 WO disclosed
WO-2022072467-A1 COMPOSITIONS, KITS AND METHODS FOR COLLECTING ANALYTE IN A SALIVA SAMPLE DECIMADX, LLC (US) 2022-04-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240024310-A1 CARBOSTYRIL DERIVATIVES AND MOOD STABILIZERS FOR TREATING MOOD DISORDERS DRD2, CHRNA6, GABRA6 DRD2 1/4885HTR1A 79/4885HTR2A 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.