Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 18/20 | 1.00 |
| ▸ | HTR1A | P08908 | 5/20 | 0.77 |
| ▸ | HTR2A | P28223 | 5/20 | 0.77 |
| ▸ | DRD3 | P35462 | 5/20 | 0.68 |
| ▸ | DRD4 | P21917 | 4/20 | 0.68 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.68 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.68 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.68 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.68 |
| ▸ | DRD1 | P21728 | 2/20 | 0.68 |
| ▸ | DRD5 | P21918 | 2/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.68 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.68 |
| ▸ | HTR1D | P28221 | 2/20 | 0.68 |
| ▸ | HTR1B | P28222 | 2/20 | 0.68 |
| ▸ | HTR2C | P28335 | 2/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.68 |
| ▸ | HTR7 | P34969 | 2/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29549434 | 1.00 | DRD2 (1.00) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL30552363 | 1.00 | DRD2 (1.00) | DRD2HTR1AHTR2ADRD3DRD4 | |
| Hydrochloric Acid SCHEMBL29365523 | 0.99 | DRD2 (0.98) | DRD2HTR1AHTR2ADRD3DRD4 | |
| Hydrochloric Acid SCHEMBL29923538 | 0.99 | DRD2 (0.98) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL30964304 | 0.99 | DRD2 (0.98) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL14587005 | 0.97 | DRD2 (0.94) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL251904 | 0.96 | DRD2 (1.00) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL253673 | 0.93 | DRD2 (1.00) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL13532797 | 0.93 | DRD2 (0.87) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL14188956 | 0.90 | DRD2 (0.82) | DRD2HTR1AHTR2ADRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112666267-B | Method for detecting related substances of aripiprazole drug substance | 上海上药中西制药有限公司 | 2023-09-26 | — | — | CN | claimed |
| CN-112666267-A | Method for detecting related substances of aripiprazole medicine | 上海上药中西制药有限公司 | 2021-04-16 | — | — | CN | claimed |
| EP-0367141-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | EP | claimed |
| US-5006528-A | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-09 | — | — | US | claimed |
| EP-0367141-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-09 | — | — | EP | claimed |
| US-20260076975-A1 | TPK AGONIST AND METHOD FOR USING SAME TO TREAT NEURODEGENERATIVE DISEASES | SHANGHAI RAISING PHARMACEUTICAL CO LTD (CN) | 2026-03-19 | — | — | US | disclosed |
| EP-4628098-A1 | TPK AGONIST AND METHOD FOR USING SAME TO TREAT NEURODEGENERATIVE DISEASES | Shanghai Raising Pharmaceutical Co., Ltd. (CN) | 2025-10-08 | — | — | EP | disclosed |
| US-20240368115-A1 | REGULATOR CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SHUJING BIOPHARMA CO., LTD (CN) | 2024-11-07 | — | — | US | disclosed |
| EP-4382521-A1 | REGULATOR CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shujing Biopharma Co., Ltd (CN) | 2024-06-12 | — | — | EP | disclosed |
| WO-2024114781-A1 | TPK AGONIST AND METHOD FOR USING SAME TO TREAT NEURODEGENERATIVE DISEASES | 上海日馨医药科技股份有限公司 | 2024-06-06 | — | — | WO | disclosed |
| US-20240024310-A1 | CARBOSTYRIL DERIVATIVES AND MOOD STABILIZERS FOR TREATING MOOD DISORDERS | OTSUKA PHARMA CO LTD (JP) | 2024-01-25 | — | — | US | disclosed |
| US-20240024310-A1 | CARBOSTYRIL DERIVATIVES AND MOOD STABILIZERS FOR TREATING MOOD DISORDERS | OTSUKA PHARMA CO LTD (JP) | 2024-01-25 | — | — | US | disclosed |
| US-20080318972-A1 | 5-HT1A RECEPTOR SUBTYPE AGONIST | OTSUKA PHARMACEUTICAL CO., LTD. | 2008-12-25 | — | — | US | disclosed |
| US-20080171752-A1 | 5-HT1A Receptor Subtype Agonist | OTSUKA PHARMACEUTICAL CO., LTD. | 2008-07-17 | — | — | US | disclosed |
| US-20080103154-A1 | 3, 4-dihydro-2(IH)-quinolinone and 2(1H)-quinolinone derivatives | CONCERT PHARMACEUTICALS INC. (US) | 2008-05-01 | — | — | US | disclosed |
| US-20080103154-A1 | 3, 4-dihydro-2(IH)-quinolinone and 2(1H)-quinolinone derivatives | CONCERT PHARMACEUTICALS INC. (US) | 2008-05-01 | — | — | US | disclosed |
| WO-2008024481-A2 | 3,4-DIHYDRO-2 (1H) - QUINOLINONE AND 2 (1H)-QUINOLINONE DERIVATIVES | CONCERT PHARMACEUTICALS INC. (US) | 2008-02-28 | — | — | WO | disclosed |
| EP-1621198-B1 | Substituted carbostyril derivatives as 5-HT 1A receptor subtype agonists | OTSUKA PHARMA CO LTD (JP) | 2007-05-23 | — | — | EP | disclosed |
| US-20070031513-A1 | Carbostyril derivatives and mood stabilizers for treating mood disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-02-08 | — | — | US | disclosed |
| US-20070031513-A1 | Carbostyril derivatives and mood stabilizers for treating mood disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240368115-A1 | REGULATOR CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | TPH1, TPH2, GAP43 | DRD2 327/4885HTR1A 29/4885HTR2A 57/4885 |
| US-20070031513-A1 | Carbostyril derivatives and mood stabilizers for treating mood disorders | CHRNA6, GABBR1, CHRNA5 | DRD2 29/4885HTR1A 151/4885HTR2A 96/4885 |
| US-20080103154-A1 | 3, 4-dihydro-2(IH)-quinolinone and 2(1H)-quinolinone derivatives | SLC6A3, HTR2C, AQP4 | DRD2 87/4885HTR1A 34/4885HTR2A 6/4885 |
| US-20080318972-A1 | 5-HT1A RECEPTOR SUBTYPE AGONIST | HTR1A, HTR5A, HTR2C | DRD2 130/4885HTR1A 1/4885HTR2A 5/4885 |
| US-20240024310-A1 | CARBOSTYRIL DERIVATIVES AND MOOD STABILIZERS FOR TREATING MOOD DISORDERS | DRD2, CHRNA6, GABRA6 | DRD2 1/4885HTR1A 79/4885HTR2A 32/4885 |
| US-20260076975-A1 | TPK AGONIST AND METHOD FOR USING SAME TO TREAT NEURODEGENERATIVE DISEASES | PDXK, NADK, HYPK | DRD2 2783/4885HTR1A 607/4885HTR2A 445/4885 |
| US-20080171752-A1 | 5-HT1A Receptor Subtype Agonist | HTR1A, HTR5A, HTR2C | DRD2 130/4885HTR1A 1/4885HTR2A 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.