Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23529948 | 1.00 | ATM (0.42) | ATML3MBTL1PDE3BPDE3AP2RY12 | |
| SCHEMBL3334122 | 0.80 | LTA4H (0.46) | HRH3GAALTA4H | |
| SCHEMBL11378355 | 0.80 | HRH3 (0.42) | HRH3LTA4H | |
| SCHEMBL11423013 | 0.78 | HRH3 (0.41) | L3MBTL1HRH3LTA4H | |
| Hydrochloric Acid SCHEMBL11382535 | 0.77 | HRH3 (0.40) | L3MBTL1HRH3LTA4H | |
| SCHEMBL23530082 | 0.77 | HRH3 (0.40) | HRH3LTA4H | |
| SCHEMBL7771160 | 0.76 | HRH3 (0.49) | PDE3BPDE3AP2RY12HRH3GAA | |
| SCHEMBL11471063 | 0.76 | LTA4H (0.46) | L3MBTL1HRH3LTA4H | |
| SCHEMBL1758566 | 0.76 | ALDH1A1 (0.40) | HRH3LTA4HAPP | |
| SCHEMBL9334195 | 0.75 | NR5A1 (0.54) | GAALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114302886-A | Triazolopyridazine derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2022-04-08 | — | — | CN | disclosed |