Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25355111 | 0.83 | DHODH (0.51) | GAALMNAKDM4EPOLBALDH1A1 | |
| SCHEMBL3846169 | 0.80 | LMNA (0.50) | GAALMNAKDM4EPOLBALDH1A1 | |
| SCHEMBL2908095 | 0.77 | GRM4 (0.47) | GAALMNAKDM4EPOLBALDH1A1 | |
| SCHEMBL3870325 | 0.75 | EGFR (0.41) | RAB9ANPC1CYP1A2 | |
| SCHEMBL5706881 | 0.75 | GAA (0.61) | GAALMNAKDM4EPOLBALDH1A1 | |
| SCHEMBL2904221 | 0.74 | ALDH1A1 (0.47) | GAALMNAKDM4EPOLBALDH1A1 | |
| SCHEMBL14970806 | 0.72 | ALDH1A1 (0.57) | GAAPOLBALDH1A1RAB9AHTT | |
| SCHEMBL2905222 | 0.72 | RAB9A (0.40) | POLBRAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL25357063 | 0.70 | DHODH (0.58) | GAALMNAKDM4EMAPK1MAPT | |
| SCHEMBL18340205 | 0.69 | HTT (0.59) | LMNAALDH1A1RAB9AMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022063303-A1 | A CLASS OF FUSED RING COMPOUNDS, AND PREPARATION AND USE THEREOF | 石药集团中奇制药技术（石家庄）有限公司 | 2022-03-31 | — | — | WO | disclosed |