Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12613764 | 0.75 | — | — | |
| SCHEMBL4196209 | 0.69 | — | — | |
| SCHEMBL360593 | 0.69 | MEN1 (0.36) | TSHRPOLBMEN1KMT2A | |
| SCHEMBL28008421 | 0.68 | TSHR (0.31) | TSHR | |
| SCHEMBL16504608 | 0.67 | CYP1A2 (0.34) | TSHRKMT2AL3MBTL1 | |
| SCHEMBL1856788 | 0.65 | L3MBTL1 (0.33) | TSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL28464466 | 0.64 | SMN1; SMN2 (0.59) | TSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL28941436 | 0.63 | ALDH1A1 (0.34) | — | |
| SCHEMBL360939 | 0.61 | — | — | |
| SCHEMBL9185491 | 0.60 | USP2 (0.41) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114302886-A | Triazolopyridazine derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2022-04-08 | — | — | CN | disclosed |