⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604137 | 0.72 | MAPK1 (0.43) | — | |
| SCHEMBL8537146 | 0.66 | MAPK1 (0.35) | — | |
| SCHEMBL7107037 | 0.61 | ALDH1A1 (0.39) | — | |
| SCHEMBL16904321 | 0.60 | KDM4E (0.31) | — | |
| SCHEMBL32689218 | 0.59 | CYP2D6 (0.41) | — | |
| SCHEMBL4880104 | 0.56 | KDM4E (0.35) | — | |
| SCHEMBL32689044 | 0.56 | CYP2D6 (0.38) | — | |
| SCHEMBL28500634 | 0.52 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL5423530 | 0.51 | P2RX7 (0.41) | — | |
| SCHEMBL21950851 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223195-B1 | Thermoplastic resin composition and shaped articles thereof | JSR CORP (JP) | 2012-03-14 | — | — | EP | disclosed |
| US-6562908-B2 | Blend of rubber reinforced thermoplastic resins, acrylic resins and thermoplastic norbornene resins; heat resistance, strength, processability, and laser marking properties | JSR CORPORATION (JP) | 2003-05-13 | — | — | US | disclosed |
| US-20020128392-A1 | Thermoplastic resin composition and shaped articles thereof | JSR CORPORATION (JP) | 2002-09-12 | — | — | US | disclosed |
| EP-1223195-A2 | Thermoplastic resin composition and shaped articles thereof | JSR Corporation (JP) | 2002-07-17 | — | — | EP | disclosed |