SCHEMBL8537146

SCHEMBL8537146

CC1(C(=O)O)C2C=CC(C2)C1(C)C(=O)OC(=O)C1(C)C2C=CC(C2)C1(C)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.35
TP53 P04637 1/20 0.35
NFKB1 P19838 1/20 0.35
CYP2C19 P33261 1/20 0.35
THPO P40225 1/20 0.35
STAT6 P42226 1/20 0.35
HIF1A Q16665 1/20 0.35
NPC1 O15118 1/20 0.35
GMNN O75496 1/20 0.35
LMNA P02545 1/20 0.35
MTOR P42345 1/20 0.35
RAB9A P51151 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4604137 0.88 MAPK1 (0.43) MAPK1TP53NFKB1CYP2C19THPO
SCHEMBL27937138 0.78 HTT (0.41) NPSR1
SCHEMBL27937137 0.78 HTT (0.41) NPSR1
SCHEMBL10477950 0.72
SCHEMBL7112716 0.69 PKM (0.34)
SCHEMBL295506 0.66
SCHEMBL3494225 0.65 MAPK1 (0.77) MAPK1TP53NFKB1CYP2C19THPO
SCHEMBL4608055 0.65 TDP1 (0.43) LMNA
SCHEMBL4880104 0.61 KDM4E (0.35) CYP2C19
SCHEMBL11757280 0.60 APLNR (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4039491-A IMPACT STRENGTH, NORBORNENE DERIVATIVE CONTAINING POLAR GROUP JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1977-08-02 US claimed
US-10329383-B2 Cyanate resin blends and radomes including them SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2019-06-25 US disclosed
US-20190112406-A1 Resins and Radomes Including Them SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION 2019-04-18 US disclosed
US-20180258223-A1 CYANATE RESIN BLENDS AND RADOMES INCLUDING THEM SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION 2018-09-13 US disclosed
WO-2018151800-A2 RADOME FABRICATION USING CYCLIC OLEFIN RESIN IN LIQUID MOLDING SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2018-08-23 WO disclosed
US-9914803-B2 Cyanate resin blends and radomes including them SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2018-03-13 US disclosed
EP-3013882-A1 CYANATE RESIN BLENDS AND RADOMES INCLUDING THEM Saint-gobain Performance Plastics Corporation (US) 2016-05-04 EP disclosed
EP-3013869-A1 RESINS AND RADOMES INCLUDING THEM Saint-gobain Performance Plastics Corporation (US) 2016-05-04 EP disclosed
US-20150002364-A1 CYANATE RESIN BLENDS AND RADOMES INCLUDING THEM SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION 2015-01-01 US disclosed
US-20150004423-A1 RESINS AND RADOMES INCLUDING THEM SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION 2015-01-01 US disclosed
WO-2014210236-A1 CYANATE RESIN BLENDS AND RADOMES INCLUDING THEM SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2014-12-31 WO disclosed
WO-2014210243-A1 RESINS AND RADOMES INCLUDING THEM SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2014-12-31 WO disclosed
EP-0847991-A1 Method for the preparation of N-(carboxyalkyl) imides DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-06-17 EP disclosed
US-4250063-A COORDINATION CATALYST COMPRISING AN ORGANIC COMPLEX OF TUNGSTEN OR MOLYBDENUM, A TITANIUM TETRAHALIDE, AND AN N-HALO IMIDE, A SULFIDE, A SULFOXIDE, OR A PHOSPHINE; POLYALKENAMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-02-10 US disclosed
US-4039491-A IMPACT STRENGTH, NORBORNENE DERIVATIVE CONTAINING POLAR GROUP JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1977-08-02 US disclosed