SCHEMBL29550650

SCHEMBL29550650

CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(N)=O)[C@@H](C)O

nearest known ligand 0.69

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 5/20 0.63
▸ KISS1R Q969F8 8/20 0.62
▸ NPY1R P25929 2/20 0.59
▸ NPY2R P49146 2/20 0.59
▸ NPY4R P50391 2/20 0.59
▸ IL23R Q5VWK5 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1579410 0.97 GHSR (0.60) GHSRKISS1RNPY1RNPY2RNPY4R
SCHEMBL29550887 0.97 IL23R (0.64) GHSRIL23R
SCHEMBL29550921 0.97 IL23R (0.64) GHSRIL23R
SCHEMBL31404052 0.95 GHSR (0.68) GHSRKISS1RNPY1RNPY2RNPY4R
SCHEMBL29550452 0.94 IL23R (0.61) IL23R
SCHEMBL29550445 0.94 GHSR (0.59) GHSRKISS1RNPY1RNPY2RNPY4R
SCHEMBL29550903 0.94 IL23R (0.62) GHSRNPY1RNPY2RNPY4RIL23R
SCHEMBL29551593 0.94 IL23R (0.65) GHSRKISS1RIL23R
SCHEMBL29550696 0.94 GHSR (0.67) GHSRKISS1R
SCHEMBL29391843 0.93 IL23R (0.65) GHSRNPY1RNPY2RNPY4RIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220047679-A1 COMBINATION THERAPY ANTISENSE THERAPEUTICS LTD (AU) 2022-02-17 — — US claimed
US-20220047679-A1 COMBINATION THERAPY ANTISENSE THERAPEUTICS LTD (AU) 2022-02-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220047679-A1 COMBINATION THERAPY GHSR, GHRHR, IGF1R GHSR 1/4885KISS1R 390/4885NPY1R 76/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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