SCHEMBL29550696

SCHEMBL29550696

C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](N)Cc1ccccc1)[C@@H](C)O)C(N)=O

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 9/20 0.67
▸ KISS1R Q969F8 4/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29550978 0.96 GHSR (0.63) GHSRKISS1R
SCHEMBL29551214 0.95 GHSR (0.63) GHSR
SCHEMBL29551293 0.95 GHSR (0.64) GHSRKISS1R
SCHEMBL30276253 0.95 GHSR (0.64) GHSRKISS1R
SCHEMBL30276276 0.94 GHSR (0.63) GHSRKISS1R
SCHEMBL29550650 0.94 GHSR (0.63) GHSRKISS1R
SCHEMBL31171030 0.93 GHSR (0.70) GHSR
SCHEMBL29551222 0.93 GHSR (0.60) GHSR
SCHEMBL29565376 0.92 GHSR (0.61) GHSRKISS1R
SCHEMBL29365946 0.92 GHSR (0.64) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220047679-A1 COMBINATION THERAPY ANTISENSE THERAPEUTICS LTD (AU) 2022-02-17 — — US claimed
US-20250154219-A1 PEPTIDE ANALOGS ADEPTHERA LLC 2025-05-15 — — US disclosed
US-12110318-B2 Peptide analogs ADEPTHERA LLC (US) 2024-10-08 — — US disclosed
US-20220324935-A1 PEPTIDE ANALOGS ADEPTHERA LLC 2022-10-13 — — US disclosed
US-11390657-B2 Peptide analogs ADEPTHERA LLC (US) 2022-07-19 — — US disclosed
US-20220047679-A1 COMBINATION THERAPY ANTISENSE THERAPEUTICS LTD (AU) 2022-02-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220047679-A1 COMBINATION THERAPY GHSR, GHRHR, IGF1R GHSR 1/4885KISS1R 390/4885
US-12110318-B2 Peptide analogs RAMP1, RAMP3, RAMP2 GHSR 63/4885KISS1R 327/4885
US-20220324935-A1 PEPTIDE ANALOGS RAMP1, RAMP2, RAMP3 GHSR 68/4885KISS1R 503/4885
US-20250154219-A1 PEPTIDE ANALOGS RAMP1, RAMP2, RAMP3 GHSR 68/4885KISS1R 503/4885
US-11390657-B2 Peptide analogs RAMP1, RAMP3, RAMP2 GHSR 63/4885KISS1R 327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback