SCHEMBL29550706

SCHEMBL29550706

C[C@@H](O)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCCCC(=O)O

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 5/20 0.59
▸ GHSR Q92847 1/20 0.59
▸ IL23R Q5VWK5 6/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29550927 1.00 KISS1R (0.59) KISS1RGHSRIL23R
SCHEMBL29550975 1.00 KISS1R (0.59) KISS1RGHSRIL23R
SCHEMBL29551307 0.97 GHSR (0.59) KISS1RGHSRIL23R
SCHEMBL29550674 0.96 GHSR (0.58) KISS1RGHSRIL23R
SCHEMBL29550709 0.94 KISS1R (0.61) KISS1RGHSRIL23R
SCHEMBL29551274 0.93 GHSR (0.60) KISS1RGHSRIL23R
SCHEMBL29551174 0.92 IL23R (0.59) KISS1RGHSRIL23R
SCHEMBL29550958 0.92 KISS1R (0.57) KISS1RIL23R
SCHEMBL29551293 0.91 GHSR (0.64) KISS1RGHSRIL23R
SCHEMBL30276253 0.91 GHSR (0.64) KISS1RGHSRIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220047679-A1 COMBINATION THERAPY ANTISENSE THERAPEUTICS LTD (AU) 2022-02-17 — — US claimed
US-20220047679-A1 COMBINATION THERAPY ANTISENSE THERAPEUTICS LTD (AU) 2022-02-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220047679-A1 COMBINATION THERAPY GHSR, GHRHR, IGF1R KISS1R 390/4885GHSR 1/4885IL23R 1067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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