Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | HTR6 | P50406 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | C1R | P00736 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21529204 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRHTR6L3MBTL1MAPT | |
| SCHEMBL23076447 | 0.83 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPTHPGDKMT2A | |
| SCHEMBL3017559 | 0.81 | ALDH1A1 (1.00) | ALDH1A1TSHRHTR6L3MBTL1MAPT | |
| SCHEMBL7669650 | 0.75 | POLB (0.81) | ALDH1A1TSHRHTR6L3MBTL1MAPT | |
| SCHEMBL21165781 | 0.75 | TSHR (0.52) | ALDH1A1TSHRMAPTHPGDKMT2A | |
| SCHEMBL7669051 | 0.73 | HTR6 (0.78) | ALDH1A1TSHRHTR6L3MBTL1MAPT | |
| SCHEMBL7669323 | 0.69 | MAPT (0.81) | ALDH1A1TSHRL3MBTL1MAPTHPGD | |
| SCHEMBL7665354 | 0.69 | ALDH1A1 (0.78) | ALDH1A1TSHRHTR6L3MBTL1MAPT | |
| SCHEMBL3756898 | 0.68 | POLB (0.84) | ALDH1A1TSHRHTR6MAPTHPGD | |
| SCHEMBL7699874 | 0.67 | MAPT (0.66) | ALDH1A1L3MBTL1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109789129-B | Autophagy-improving material and use thereof | 延世大学校产学协力团 | 2022-04-29 | — | — | CN | disclosed |