Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23076447 | 0.87 | ALDH1A1 (0.58) | TSHRMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL21529204 | 0.75 | ALDH1A1 (0.67) | TSHRMAPTALDH1A1HPGDKMT2A | |
| SCHEMBL21165774 | 0.73 | TSHR (0.54) | TSHRMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL23867528 | 0.71 | MAPT (0.64) | TSHRMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL29039874 | 0.68 | HSD11B1 (0.62) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7694685 | 0.67 | MEN1 (1.00) | TSHRMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL25010121 | 0.67 | ALDH1A1 (1.00) | TSHRMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL7702622 | 0.67 | ALDH1A1 (0.59) | TSHRMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL7701075 | 0.66 | MEN1 (0.82) | TSHRMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL7669614 | 0.66 | MAPT (0.82) | TSHRMAPTALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868043-B | Novel benzenesulfonyl oxazole derivative and use thereof | 利索科技股份有限公司 | 2023-11-14 | — | — | CN | claimed |
| US-11345671-B2 | Phenylsulfonyl oxazole derivative and use thereof | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2022-05-31 | — | — | US | claimed |
| US-20210070718-A1 | NOVEL PHENYLSULFONYL OXAZOLE DERIVATIVE AND USE THEREOF | LYSOTECH INC. (KR) | 2021-03-11 | — | — | US | claimed |
| CN-111868043-A | Novel benzenesulfonyl oxazole derivatives and use thereof | 庆北大学校产学协力团 | 2020-10-30 | — | — | CN | claimed |
| CN-111868043-B | Novel benzenesulfonyl oxazole derivative and use thereof | 利索科技股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| US-11345671-B2 | Phenylsulfonyl oxazole derivative and use thereof | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2022-05-31 | — | — | US | disclosed |
| US-11345671-B2 | Phenylsulfonyl oxazole derivative and use thereof | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2022-05-31 | — | — | US | disclosed |
| US-20210070718-A1 | NOVEL PHENYLSULFONYL OXAZOLE DERIVATIVE AND USE THEREOF | LYSOTECH INC. (KR) | 2021-03-11 | — | — | US | disclosed |
| US-20210070718-A1 | NOVEL PHENYLSULFONYL OXAZOLE DERIVATIVE AND USE THEREOF | LYSOTECH INC. (KR) | 2021-03-11 | — | — | US | disclosed |
| CN-111868043-A | Novel benzenesulfonyl oxazole derivatives and use thereof | 庆北大学校产学协力团 | 2020-10-30 | — | — | CN | disclosed |
| WO-2019139365-A1 | NOVEL PHENYLSULFONYL OXAZOLE DERIVATIVE AND USE THEREOF | 경북대학교 산학협력단 | 2019-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210070718-A1 | NOVEL PHENYLSULFONYL OXAZOLE DERIVATIVE AND USE THEREOF | PSEN1, PSEN2, PARK7 | TSHR 4679/4885MAPT 17/4885ALDH1A1 194/4885 |
| US-11345671-B2 | Phenylsulfonyl oxazole derivative and use thereof | PSEN1, OXA1L, PARK7 | TSHR 4695/4885MAPT 54/4885ALDH1A1 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.