SCHEMBL29550957

SCHEMBL29550957

CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CS)NC(=O)[C@H](N)Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

nearest known ligand 0.70

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 2/20 0.64
▸ GHSR Q92847 2/20 0.64
▸ IL23R Q5VWK5 10/20 0.63
▸ UTS2R Q9UKP6 1/20 0.63
▸ NPY1R P25929 2/20 0.61
▸ NPY2R P49146 2/20 0.61
▸ NPY4R P50391 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29550946 1.00 KISS1R (0.64) KISS1RGHSRIL23RUTS2RNPY1R
SCHEMBL31404052 0.97 GHSR (0.68) KISS1RGHSRNPY1RNPY2RNPY4R
SCHEMBL29550921 0.95 IL23R (0.64) GHSRIL23R
SCHEMBL29550887 0.95 IL23R (0.64) GHSRIL23R
SCHEMBL29551304 0.95 UTS2R (0.61) KISS1RGHSRIL23RUTS2RNPY1R
SCHEMBL31619561 0.95 IL23R (0.59) KISS1RGHSRIL23RUTS2R
SCHEMBL29972966 0.95 IL23R (0.59) KISS1RGHSRIL23RUTS2R
SCHEMBL31619560 0.95 IL23R (0.59) KISS1RGHSRIL23RUTS2R
SCHEMBL31619556 0.94 IL23R (0.61) KISS1RGHSRIL23RUTS2R
SCHEMBL31619566 0.93 IL23R (0.61) IL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220047679-A1 COMBINATION THERAPY ANTISENSE THERAPEUTICS LTD (AU) 2022-02-17 — — US claimed
US-20220047679-A1 COMBINATION THERAPY ANTISENSE THERAPEUTICS LTD (AU) 2022-02-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220047679-A1 COMBINATION THERAPY GHSR, GHRHR, IGF1R KISS1R 390/4885GHSR 1/4885IL23R 1067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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