Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | RECQL | P46063 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1060620 | 1.00 | MAPT (0.67) | MAPTALDH1A1RECQLKMT2AKDM4E | |
| SCHEMBL1079739 | 0.84 | MAPT (0.68) | MAPTALDH1A1RECQLKMT2AKDM4E | |
| SCHEMBL1079740 | 0.84 | MAPT (0.68) | MAPTALDH1A1RECQLKMT2AKDM4E | |
| SCHEMBL16281039 | 0.84 | MAPT (0.68) | MAPTALDH1A1RECQLKMT2AKDM4E | |
| SCHEMBL24213670 | 0.82 | MAPT (0.67) | MAPTALDH1A1RECQLKMT2AKDM4E | |
| SCHEMBL128686 | 0.82 | MAPT (0.67) | MAPTALDH1A1RECQLKMT2AKDM4E | |
| 1-Methyltryptophan SCHEMBL14202956 | 0.82 | MAPT (0.71) | MAPTALDH1A1RECQLKMT2AKDM4E | |
| SCHEMBL22807019 | 0.82 | MAPT (0.67) | MAPTALDH1A1RECQLKMT2AKDM4E | |
| SCHEMBL20038781 | 0.82 | MAPT (0.67) | MAPTALDH1A1RECQLKMT2AKDM4E | |
| SCHEMBL5281301 | 0.82 | MAPT (0.67) | MAPTALDH1A1RECQLKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220047679-A1 | COMBINATION THERAPY | ANTISENSE THERAPEUTICS LTD (AU) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220047679-A1 | COMBINATION THERAPY | GHSR, GHRHR, IGF1R | MAPT 4374/4885ALDH1A1 4566/4885RECQL 1419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.