Sugi Predict

Sugi Predict / Compounds / SCHEMBL128686

SCHEMBL128686

SCHEMBL128686

N[C@H](Cc1cn(Cl)c2ccccc12)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.67
▸ ALDH1A1 P00352 2/20 0.67
▸ RECQL P46063 2/20 0.67
▸ PTGS2 P35354 1/20 0.53
▸ SCN9A Q15858 1/20 0.51
▸ KMT2A Q03164 3/20 0.50
▸ KDM4E B2RXH2 3/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ LMNA P02545 2/20 0.50
▸ BLM P54132 2/20 0.50
▸ PMP22 Q01453 2/20 0.50
▸ HIF1A Q16665 2/20 0.50
▸ MPO P05164 1/20 0.50
▸ TSHR P16473 1/20 0.50
▸ NOS3 P29474 3/20 0.48
▸ NOS1 P29475 3/20 0.48
▸ NOS2 P35228 3/20 0.48
▸ PKM P14618 2/20 0.47
▸ ALPI P09923 1/20 0.47
▸ PTGS1 P23219 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1059011 1.00 MAPT (0.67) MAPTALDH1A1RECQLPTGS2SCN9A
SCHEMBL5281301 1.00 MAPT (0.67) MAPTALDH1A1RECQLPTGS2SCN9A
SCHEMBL16281039 0.87 MAPT (0.68) MAPTALDH1A1RECQLPTGS2SCN9A
SCHEMBL29982985 0.84 ALDH1A1 (0.65) MAPTALDH1A1RECQLPTGS2SCN9A
SCHEMBL1079739 0.84 MAPT (0.68) MAPTALDH1A1RECQLPTGS2SCN9A
SCHEMBL1079740 0.84 MAPT (0.68) MAPTALDH1A1RECQLPTGS2SCN9A
SCHEMBL11033128 0.83 KMT2A (0.69) MAPTALDH1A1RECQLKMT2ALMNA
SCHEMBL9584445 0.83 KMT2A (0.69) MAPTALDH1A1RECQLKMT2ALMNA
SCHEMBL24213670 0.82 MAPT (0.67) MAPTALDH1A1RECQLPTGS2SCN9A
SCHEMBL20038781 0.82 MAPT (0.67) MAPTALDH1A1RECQLPTGS2SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 631 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240188613-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-06-13 — — US claimed
US-20240090547-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-03-21 — — US claimed
US-20240065302-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-02-29 — — US claimed
CN-116963609-A Sweetener composition comprising mogrosides and uses thereof 弗门尼舍公司 2023-10-27 — — CN claimed
EP-4258896-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF Firmenich Incorporated (US) 2023-10-18 — — EP claimed
EP-4258895-A1 SWEETENER COMPOSTIONS COMPRISING SIAMENOSIDE I AND USES THEREOF Firmenich Incorporated (US) 2023-10-18 — — EP claimed
EP-4258897-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF Firmenich Incorporated (US) 2023-10-18 — — EP claimed
WO-2022155669-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED (US) 2022-07-21 — — WO claimed
WO-2022155668-A1 SWEETENER COMPOSTIONS COMPRISING SIAMENOSIDE I AND USES THEREOF FIRMENICH INCORPORATED (US) 2022-07-21 — — WO claimed
WO-2022155667-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED (US) 2022-07-21 — — WO claimed
US-20180086751-A1 SWEETENER COMPOSITION SENOMYX, INC. 2018-03-29 — — US claimed
US-20170354175-A1 SWEETENER COMPOSITION SENOMYX, INC. 2017-12-14 — — US claimed
US-20170105432-A1 SWEETENER AND FLAVOR ENHANCER FORMULATIONS SENOMYX, INC. 2017-04-20 — — US claimed
US-20110045547-A1 ISOMERASES AND EPIMERASES AND METHODS OF USING DE SOUZA MERVYN L 2011-02-24 — — US claimed
WO-2011002469-A1 ISOMERASES AND EPIMERASES AND METHODS OF USING CARGILL, INCORPORATED (US) 2011-01-06 — — WO claimed
EP-2225390-A1 AMINOTRANSFERASE AND OXIDOREDUCTASE NUCLEIC ACIDS AND POLYPEPTIDES AND METHODS OF USING Cargill, Incorporated (US) 2010-09-08 — — EP claimed
WO-2009088482-A1 AMINOTRANSFERASE AND OXIDOREDUCTASE NUCLEIC ACIDS AND POLYPEPTIDES AND METHODS OF USING CARGILL, INCORPORATED (US) 2009-07-16 — — WO claimed
WO-2009088442-A2 ISOMERASES AND EPIMERASES AND METHODS OF USING CARGILL, INCORPORATED (US) 2009-07-16 — — WO claimed
US-20260144275-A1 EXTRUSION METHODS AND FLAVORED PRODUCTS FORMED THEREBY FIRMENICH SA (CH) 2026-05-28 — — US disclosed
EP-1826267-A1 Novel halogenases Combinature Biopharm AG (DE) 2007-08-29 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144275-A1 EXTRUSION METHODS AND FLAVORED PRODUCTS FORMED THEREBY MYCBP, VIM, MAFG MAPT 463/4885ALDH1A1 1278/4885RECQL 3604/4885
US-20180086751-A1 SWEETENER COMPOSITION TAS2R50, TAS1R2, TAS2R10 MAPT 1902/4885ALDH1A1 328/4885RECQL 3952/4885
US-20170105432-A1 SWEETENER AND FLAVOR ENHANCER FORMULATIONS TAS2R50, TAS2R10, TAS2R40 MAPT 3082/4885ALDH1A1 390/4885RECQL 4077/4885
US-20170354175-A1 SWEETENER COMPOSITION TAS1R2, TAS1R1, TAS2R50 MAPT 2023/4885ALDH1A1 343/4885RECQL 3935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.