Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 6/20 | 0.52 |
| ▸ | ALPL | P05186 | 5/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adrenalone SCHEMBL123124 | 0.81 | ALPG (0.55) | ALPGALPLPTGS2KDM4EMAPT | |
| Adrenalone SCHEMBL29550997 | 0.81 | ALPG (0.55) | ALPGALPLPTGS2KDM4EMAPT | |
| SCHEMBL25640423 | 0.81 | ERCC1 (0.58) | ALPGALPLPTGS2KDM4EMAPT | |
| Adrenalone SCHEMBL6662605 | 0.80 | ALPG (0.54) | ALPGALPLPTGS2KDM4EMAPT | |
| SCHEMBL7436867 | 0.79 | HSD17B3 (0.52) | ALPGKDM4EMAPTALDH1A1BLM | |
| SCHEMBL6046293 | 0.79 | ALPG (0.52) | ALPGALPLPTGS2KDM4EMAPT | |
| Adrenalone SCHEMBL28668200 | 0.79 | ALPG (0.52) | ALPGALPLPTGS2KDM4EMAPT | |
| SCHEMBL14646958 | 0.78 | ALPG (0.51) | ALPGALPLPTGS2KDM4EMAPT | |
| SCHEMBL8558279 | 0.78 | CA12 (0.46) | ALPGALPLPTGS2KDM4EMAPT | |
| SCHEMBL9768178 | 0.77 | KDM4E (0.53) | ALPGALPLPTGS2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |