Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | DBH | P09172 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 3/20 | 0.51 |
| ▸ | ALPG | P10696 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA7 | P43166 | 4/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29391092 | 1.00 | KDM4E (0.53) | KDM4EGAADBHRECQLALPL | |
| Hydrochloric Acid SCHEMBL11290306 | 0.98 | KDM4E (0.51) | KDM4EGAADBHRECQLALPL | |
| SCHEMBL9768009 | 0.85 | KDM4E (0.49) | KDM4EGAADBHRECQLALPL | |
| SCHEMBL31419983 | 0.80 | ADRB2 (0.51) | KDM4EGAARECQLALPGCA12 | |
| Adrenalone SCHEMBL123124 | 0.80 | ALPG (0.55) | KDM4EGAADBHRECQLALPL | |
| Adrenalone SCHEMBL29550997 | 0.80 | ALPG (0.55) | KDM4EGAADBHRECQLALPL | |
| SCHEMBL9768252 | 0.80 | KDM4E (0.50) | KDM4EGAADBHRECQLALPL | |
| SCHEMBL25640423 | 0.80 | ERCC1 (0.58) | KDM4EGAADBHRECQLALPL | |
| SCHEMBL21579056 | 0.79 | ADRB3 (0.62) | ADRB3ADRA1A | |
| SCHEMBL10071964 | 0.79 | SIGMAR1 (0.53) | ALPLALPGADRB2ADRB1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555042-B1 | PROCESS FOR PREPARATION OF ISOPROTERENOL HYDROCHLORIDE | EMCURE PHARMACEUTICALS LTD (IN) | 2021-07-21 | — | — | EP | claimed |
| US-10759738-B2 | Process for preparation of isoproterenol hydrochloride | EMCURE PHARMACEUTICALS LIMITED (IN) | 2020-09-01 | — | — | US | claimed |
| EP-3555042-A1 | PROCESS FOR PREPARATION OF ISOPROTERENOL HYDROCHLORIDE | Emcure Pharmaceuticals Limited (IN) | 2019-10-23 | — | — | EP | claimed |
| WO-2018127806-A1 | PROCESS FOR PREPARATION OF ISOPROTERENOL HYDROCHLORIDE | EMCURE PHARMACEUTICALS LIMITED (IN) | 2018-07-12 | — | — | WO | claimed |
| EP-3555042-B1 | PROCESS FOR PREPARATION OF ISOPROTERENOL HYDROCHLORIDE | EMCURE PHARMACEUTICALS LTD (IN) | 2021-07-21 | — | — | EP | disclosed |
| EP-3555042-B1 | PROCESS FOR PREPARATION OF ISOPROTERENOL HYDROCHLORIDE | EMCURE PHARMACEUTICALS LTD (IN) | 2021-07-21 | — | — | EP | disclosed |
| US-10759738-B2 | Process for preparation of isoproterenol hydrochloride | EMCURE PHARMACEUTICALS LIMITED (IN) | 2020-09-01 | — | — | US | disclosed |
| US-10759738-B2 | Process for preparation of isoproterenol hydrochloride | EMCURE PHARMACEUTICALS LIMITED (IN) | 2020-09-01 | — | — | US | disclosed |
| EP-3555042-A1 | PROCESS FOR PREPARATION OF ISOPROTERENOL HYDROCHLORIDE | Emcure Pharmaceuticals Limited (IN) | 2019-10-23 | — | — | EP | disclosed |
| EP-3555042-A1 | PROCESS FOR PREPARATION OF ISOPROTERENOL HYDROCHLORIDE | Emcure Pharmaceuticals Limited (IN) | 2019-10-23 | — | — | EP | disclosed |
| WO-2018127806-A1 | PROCESS FOR PREPARATION OF ISOPROTERENOL HYDROCHLORIDE | EMCURE PHARMACEUTICALS LIMITED (IN) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018127806-A1 | PROCESS FOR PREPARATION OF ISOPROTERENOL HYDROCHLORIDE | EMCURE PHARMACEUTICALS LIMITED (IN) | 2018-07-12 | — | — | WO | disclosed |
| US-20140329907-A1 | CATECHOLAMINE DERIVATIVES FOR OBESITY AND NEUROLOGICAL DISORDERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-11-06 | — | — | US | disclosed |
| US-20120022086-A1 | CATECHOLAMINE DERIVATIVES FOR OBESITY AND NEUROLOGICAL DISORDERS | EMORY UNIVERSITY (US) | 2012-01-26 | — | — | US | disclosed |
| WO-2010107866-A2 | CATECHOLAMINE DERIVATIVES FOR OBESITY AND NEUROLOGICAL DISORDERS | EMORY UNIVERSITY (US) | 2010-09-23 | — | — | WO | disclosed |
| US-5047592-A | Selective hydrogenolysis process | ETHYL CORPORATION (US) | 1991-09-10 | — | — | US | disclosed |
| US-4594356-A | Topical administering an adrenalone derivative | KEY PHARMACEUTICALS, INC. (US) | 1986-06-10 | — | — | US | disclosed |
| US-4147799-A | Process for reducing blood pressure and blocking β-adrenergic receptor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1979-04-03 | — | — | US | disclosed |
| US-4094983-A | \"KETO\" SYMPATHOMIMETIC AMINES | INTERX RESEARCH CORPORATION (US) | 1978-06-13 | — | — | US | disclosed |
| US-3922348-A | 3{40 ,4{40 -Dihydroxy-2-(isopropylamino)acetophenone intraocular pressure lowering process | MEAD JOHNSON & CO | 1975-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022086-A1 | CATECHOLAMINE DERIVATIVES FOR OBESITY AND NEUROLOGICAL DISORDERS | BDNF, NTRK2, COMT | KDM4E 2077/4885GAA 294/4885DBH 14/4885 |
| US-10759738-B2 | Process for preparation of isoproterenol hydrochloride | ADRA1A, ADRB1, ADRA2C | KDM4E 2624/4885GAA 2476/4885DBH 52/4885 |
| US-20140329907-A1 | CATECHOLAMINE DERIVATIVES FOR OBESITY AND NEUROLOGICAL DISORDERS | BDNF, NTRK2, COMT | KDM4E 2077/4885GAA 294/4885DBH 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.