Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 6/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24282593 | 1.00 | GPR119 (0.39) | GPR119TSHRALOX15KDM1ANAMPT | |
| SCHEMBL29550726 | 1.00 | GPR119 (0.39) | GPR119TSHRALOX15KDM1ANAMPT | |
| SCHEMBL23046171 | 1.00 | GPR119 (0.39) | GPR119TSHRALOX15KDM1ANAMPT | |
| SCHEMBL23024208 | 0.89 | F11 (0.32) | — | |
| SCHEMBL23024207 | 0.89 | F11 (0.32) | — | |
| SCHEMBL30568087 | 0.88 | GPR119 (0.39) | GPR119TSHRALOX15NAMPTEGLN2 | |
| SCHEMBL23508820 | 0.86 | GPR119 (0.39) | GPR119TSHRALOX15KDM1ANAMPT | |
| SCHEMBL23046244 | 0.86 | GPR119 (0.39) | GPR119TSHRALOX15KDM1ANAMPT | |
| SCHEMBL23046243 | 0.86 | GPR119 (0.39) | GPR119TSHRALOX15KDM1ANAMPT | |
| SCHEMBL29892178 | 0.86 | GPR119 (0.39) | GPR119TSHRALOX15KDM1ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3984999-A1 | SHP2 PHOSPHATASE ALLOSTERIC INHIBITOR | Beijing Shenogen Pharma Group Ltd. (CN) | 2022-04-20 | — | — | EP | disclosed |