Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29922526 | 1.00 | MAPT (0.40) | MAPTPOLBCYP3A4TP53MAPK1 | |
| SCHEMBL8731622 | 1.00 | MAPT (0.40) | MAPTPOLBCYP3A4TP53MAPK1 | |
| SCHEMBL30498603 | 0.83 | MAPT (0.41) | MAPTPOLBCYP3A4TP53MAPK1 | |
| SCHEMBL30498601 | 0.83 | MAPT (0.38) | MAPTPOLBCYP3A4TP53MAPK1 | |
| SCHEMBL8733660 | 0.80 | TTL (0.39) | MAPTPOLBCYP3A4TP53MAPK1 | |
| SCHEMBL8731624 | 0.77 | MAPT (0.40) | MAPTPOLBCYP3A4MEN1KMT2A | |
| SCHEMBL8731628 | 0.71 | ALDH1A1 (0.57) | MAPTPOLBCYP3A4MEN1KMT2A | |
| SCHEMBL18089046 | 0.71 | ALDH1A1 (0.57) | MAPTPOLBCYP3A4MEN1KMT2A | |
| SCHEMBL9549996 | 0.71 | ALDH1A1 (0.57) | MAPTPOLBCYP3A4MEN1KMT2A | |
| SCHEMBL15220009 | 0.71 | ALDH1A1 (0.57) | MAPTPOLBCYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119923399-A | Useful as matrix metalloproteinase inhibitors diazabicyclooctane derivatives of (a) | 瓦萨治疗有限责任公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-119731179-A | IKZF2 degradation agent and application thereof | 密歇根大学董事会 | 2025-03-28 | — | — | CN | disclosed |
| CN-119630656-A | Heterocyclic compounds for inducing cleavage of mutant KRAS proteins | 安斯泰来制药株式会社 | 2025-03-14 | — | — | CN | disclosed |
| CN-119433222-A | Recovery method and recovery device for metal in photovoltaic module welding strip | 天合光能股份有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-115181092-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117320715-A | Compounds for the treatment of hyperproliferative diseases | 瓦尔希伯伦私人肿瘤研究基金会 | 2023-12-29 | — | — | CN | disclosed |
| CN-117042759-A | IL-31 production inhibitor and pharmaceutical composition containing the same | 国立大学法人九州大学 | 2023-11-10 | — | — | CN | disclosed |
| CN-116888101-A | Substituted isoxazoline derivatives | 巴斯夫欧洲公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116018344-A | Pesticidally active heterocyclic derivatives with sulfur containing substituents | 先正达农作物保护股份公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-110271331-B | Pressure-sensitive transfer printing correction tape | 株式会社蜻蜓铅笔 | 2022-11-08 | — | — | CN | disclosed |
| CN-114591302-B | Compounds and methods for preparing compounds | 北京远大九和药业有限公司 | 2022-10-28 | — | — | CN | disclosed |
| WO-2022215387-A1 | HYDROPONIC CULTIVATION METHOD | 国立研究開発法人農業・食品産業技術総合研究機構 | 2022-10-13 | — | — | WO | disclosed |
| CN-112279837-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-114787159-A | BRM targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-110204544-B | 2- (morpholin-4-yl) -1, 7-naphthyridine | 拜耳制药股份公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-110088103-B | Novel tetrahydropyridopyrimidine compounds for the treatment and prophylaxis of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2022-04-12 | — | — | CN | disclosed |